Results 111 to 120 of about 11,822,869 (333)

The impact of the 1938 fascist anti-Semitic legislation on the development of physiology in Italian universities following replacement of five full professors

Advances in Physiology Education
The effects of the 1938 fascist anti-Semitic laws on the development of physiology in Italy are discussed, focusing on the replacement of five full professors of human physiology expelled from the Universities of Bologna, Milan, Turin, Genoa, and Palermo.
Pompeo Volpe, Carlo Reggiani, Aram Megighian   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Human anotomy and physiology

, 1980
xv+887hlm ...
SILVERSTEIN, ALVIN
core  

The ins and outs of liver fat metabolism: The effect of phenotype and diet on risk of intrahepatic triglyceride accumulation

Experimental Physiology
In health, the liver is a metabolically flexible organ that plays a key role in regulating systemic lipid and glucose concentrations. There is a constant flux of fatty acids (FAs) to the liver from multiple sources, including adipose tissue, dietary ...
Kieran Smith, Kaitlyn M. J. H. Dennis, Leanne Hodson   +2 more
doaj   +1 more source

The Effect of Physical Activity on Cytokine Production: A Systematic Parallel Study of Horse and Human Athletes

International Journal of Equine Science
Cytokines are glycoproteins responsible for cellular communication, influenced by exercise. Their levels vary depending on the intensity and type of physical activity in both humans and horses. This review aimed to assess the effects of various types and
Ifeoluwa Peace Oladapo, Abolaji Samson Olagunju, Olalekan Chris Akinsulie, Eduarda Proença, Ursula Yaeko Yoshitani, Marcelo Beltrão Molento   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Human physiology in extreme environments /

Human Physiology in Extreme Environments is the one publication that offers how human biology and physiology is affected by extreme environments while highlighting technological innovations that allow us to adapt and regulate environments.
Opatz, Oliver,author., Stahn, Alexander Christoph,author., Gunga, Hanns-Christian,author., Steinach, Mathias,author.   +3 more
core  

Effect of nasopharyngeal airway on hypoxemia in overweight and obese patients undergoing sedated endoscopy: A randomized trial

iScience
Summary: Hypoxemia is common during sedated gastrointestinal endoscopy (SGIE), especially in overweight and obese patients, yet the effectiveness of nasopharyngeal airways (NAs) for prevention remains unclear.
Hai-Ding Zou, Qing Liu, Jie Zhang, Yun-Xuan Huang, Zhao-Lan Hu, Pei Zhou, Cong Luo, Ru-Yi Luo   +7 more
doaj   +1 more source

Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a

Nature Communications, 2017
Metabolic diseases have been associated with cognitive impairment. Here, the authors show that brain insulin resistance induced by high-fat diet leads to increased palmitoylation of AMPA receptors and thus changes in hippocampal plasticity, learning and ...
Matteo Spinelli, Salvatore Fusco, Marco Mainardi, Federico Scala, Francesca Natale, Rosita Lapenta, Andrea Mattera, Marco Rinaudo, Domenica Donatella Li Puma, Cristian Ripoli, Alfonso Grassi, Marcello D’Ascenzo, Claudio Grassi   +12 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source