Results 191 to 200 of about 1,669,866 (339)

Pharmacological and physiological assessment of serotonin formation and degradation in isolated preparations from mouse and human hearts [PDF]

, 2017
Ulrich Gergs, Franziska Jung, Igor Buchwalow, Britt Hofmann, Andreas Simm, Hendrik Treede, Joachim Neumann   +6 more
openalex   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Does Gut Microbial Methylglyoxal Metabolism Impact Human Physiology? [PDF]

Antioxidants (Basel)
Akinrimisi OI, Maasen K, Scheijen JLJM, Nemet I, Nieuwdorp M, Schalkwijk CG, Hanssen NMJ.   +6 more
europepmc   +1 more source

The impact of integrating oral health education into a human physiology curriculum for students of early childhood education. [PDF]

J Dent Sci, 2022
Lee MC, Wang LH, Lin TC, Chang YT, Cheng FC, Chiang CP.   +5 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Adapting a Human Physiology Teaching Laboratory to the At-Home Education Setting. [PDF]

Biomed Eng Educ, 2022
Ong V, Yamashiro S.
europepmc   +1 more source

Consideration of physiological response in numerical models of temperature during MRI of the human head [PDF]

, 2008
Zhangwei Wang, James C. Lin, J. Thomas Vaughan, Christopher M. Collins   +3 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The Two-Pore Channel 2 in Human Physiology and Diseases: Functional Characterisation and Pharmacology. [PDF]

Int J Mol Sci
Lagostena L, Minicozzi V, Meucci M, Gradogna A, Milenkovic S, Palombi F, Ceccarelli M, Filippini A, Carpaneto A.   +8 more
europepmc   +1 more source

Medical Image and Physics Analysis of Human Physiology and Dysfunction. [PDF]

Pak J Med Sci, 2021
Wu S, Li H.
europepmc   +1 more source