Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Across species: A comparative perspective on red cell homeostasis and its influence on our understanding of human physiology and disease. [PDF]
Connolly KM +5 more
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Impacts of Changes in Atmospheric O2 on Human Physiology. Is There a Basis for Concern? [PDF]
Keeling RF +4 more
europepmc +1 more source
Why We Do It: An Elementary Discussion of Human Conduct and Related Physiology
Mason, Edward Charles, 1891-
openalex +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
A Biochemical View on Intermittent Fasting's Effects on Human Physiology-Not Always a Beneficial Strategy. [PDF]
Zambuzzi WF +3 more
europepmc +1 more source
Mice as experimental models for human physiology: when several degrees in housing temperature matter. [PDF]
Seeley RJ, MacDougald OA.
europepmc +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Autonomous slip control inspired by human physiology for improved shared control strategy. [PDF]
Matos J, Capsi-Morales P, Piazza C.
europepmc +1 more source

