Results 21 to 30 of about 8,792,528 (401)

Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta

Viruses, 2022
Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta.
Yan-Na Xiao, Fei-Yuan Yu, Qian Xu, Jiang Gu   +3 more
doaj   +1 more source

Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Mesenchymal Stem/Stromal Cells Derived from Human Placenta

Frontiers in Cell and Developmental Biology, 2022
Mesenchymal stem/stromal cells derived from placenta (PMSCs) are an attractive source for regenerative medicine because of their multidifferentiation potential and immunomodulatory capabilities.
Jinlu Li, Jinlu Li, Quanlei Wang, Quanlei Wang, Yanru An, Xiaoyan Chen, Yanan Xing, Yanan Xing, Qiuting Deng, Qiuting Deng, Zelong Li, Zelong Li, Shengpeng Wang, Shengpeng Wang, Xi Dai, Xi Dai, Ning Liang, Yong Hou, Huanming Yang, Huanming Yang, Zhouchun Shang, Zhouchun Shang, Zhouchun Shang   +22 more
doaj   +1 more source

The RNA landscape of the human placenta in health and disease

Nature Communications, 2021
The placenta is the interface between mother and fetus and inadequate function contributes to short and long-term ill-health. The placenta is absent from most large-scale RNA-Seq datasets.
S. Gong, F. Gaccioli, J. Dopierala, U. Sovio, E. Cook, P. Volders, L. Martens, Paul D. W. Kirk, S. Richardson, Gordon C. S. Smith, D. S. Charnock-Jones   +10 more
semanticscholar   +1 more source

ANNEXIN A1: Roles in Placenta, Cell Survival, and Nucleus

Cells, 2022
The unbiased approaches of the last decade have enabled the collection of new data on the biology of annexin A1 (ANXA1) in a variety of scientific aspects, creating opportunities for new biomarkers and/or therapeutic purposes.
Stefanie Oliveira de Sousa, Mayk Ricardo dos Santos, Samuel Cota Teixeira, Eloisa Amália Vieira Ferro, Sonia Maria Oliani   +4 more
doaj   +1 more source

Transcriptomic Profiling of Human Placenta in Gestational Diabetes Mellitus at the Single-Cell Level

Frontiers in Endocrinology, 2021
Gestational diabetes mellitus (GDM) is associated with an increased risk of adverse pregnancy outcomes. Increasing evidence shows that placentation defects may play important roles in GDM. However, our understanding of the human placenta remains limited.
Yuqi Yang, F. Guo, Yue Peng, Rong Chen, Wenbo Zhou, Huihui Wang, J. Ouyang, Bin Yu, Zhengfeng Xu   +8 more
semanticscholar   +1 more source

Establishment of the fetal-maternal interface: developmental events in human implantation and placentation

Frontiers in Cell and Developmental Biology, 2023
Early pregnancy is a complex and well-orchestrated differentiation process that involves all the cellular elements of the fetal-maternal interface. Aberrant trophoblast-decidual interactions can lead to miscarriage and disorders that occur later in ...
Chien-Chu Huang, Ya-Wen Hsueh, Chia-Wei Chang, Hsi-Chen Hsu, Tung-Chuan Yang, Wu-Chou Lin, Hsun-Ming Chang   +6 more
doaj   +1 more source

Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome

Frontiers in Cell and Developmental Biology, 2021
Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno, Triin Kikas, Kristiina Lillepea, Maris Laan   +3 more
doaj   +1 more source

Single cell transcriptome research in human placenta [PDF]

Reproduction, 2020
Human placenta is a complex and heterogeneous organ interfacing between the mother and the fetus that supports fetal development. Alterations to placental structural components are associated with various pregnancy complications.
Hui Li, Qianhui Huang, Yu Liu, L. Garmire   +3 more
semanticscholar   +1 more source

Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells [PDF]

, 2010
Background: Genomic imprinting of the largest known cluster, the Kcnq1/KCNQ1 domain on mChr7/hChr11, displays significant differences between mouse and man.
Frost, J.M., Moore, G.E., Moore, H.D., Udayashankar, R.   +3 more
core   +9 more sources

Integrating High-Throughput Approaches and in vitro Human Trophoblast Models to Decipher Mechanisms Underlying Early Human Placenta Development

Frontiers in Cell and Developmental Biology, 2021
The placenta is a temporary but pivotal organ for human pregnancy. It consists of multiple specialized trophoblast cell types originating from the trophectoderm of the blastocyst stage of the embryo.
Bum-Kyu Lee, Jonghwan Kim
doaj   +1 more source