Results 11 to 20 of about 223,303 (264)

Uptake of Cerium Dioxide Nanoparticles and Impact on Viability, Differentiation and Functions of Primary Trophoblast Cells from Human Placenta

Nanomaterials, 2020
The human placenta is at the interface between maternal and fetal circulations, and is crucial for fetal development. The nanoparticles of cerium dioxide (CeO2 NPs) from air pollution are an unevaluated risk during pregnancy.
Margaux Nedder, Sonja Boland, Stéphanie Devineau, Amal Zerrad-Saadi, Jasmina Rogozarski, René Lai-Kuen, Ibtissem Baya, Jean Guibourdenche, Francoise Vibert, Audrey Chissey, Sophie Gil, Xavier Coumoul, Thierry Fournier, Ioana Ferecatu   +13 more
doaj   +1 more source

Development of the human placenta [PDF]

Development, 2019
ABSTRACT The placenta is essential for normal in utero development in mammals. In humans, defective placental formation underpins common pregnancy disorders such as pre-eclampsia and fetal growth restriction. The great variation in placental types across mammals means that animal models have been of limited use in understanding human ...
Turco, Margherita Y, Moffett, Ashley
openaire   +3 more sources

Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts

PPAR Research, 2020
Trophoblasts, as the cells that make up the main part of the placenta, undergo cell differentiation processes such as invasion, migration, and fusion.
Fulin Liu, Christine Rouault, Mickael Guesnon, Wencan Zhu, Karine Clément, Séverine A. Degrelle, Thierry Fournier   +6 more
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Immunosuppressive Protein Signatures Carried by Syncytiotrophoblast-Derived Exosomes and Their Role in Human Pregnancy

Frontiers in Immunology, 2021
The syncytiotrophoblast (STB) of human placenta constitutively and throughout pregnancy produces and secretes exosomes - nanometer-sized membrane-bound extracellular vesicles from the endosomal compartment that convey cell-cell contact ‘by proxy ...
Lucia Mincheva-Nilsson
doaj   +1 more source

The human placenta methylome [PDF]

Proceedings of the National Academy of Sciences, 2013
Tissue-specific DNA methylation is found at promoters, enhancers, and CpG islands but also over larger genomic regions. In most human tissues, the vast majority of the genome is highly methylated (>70%). Recently, sequencing of bisulfite-treated DNA (MethylC-seq) has revealed large partially methylated domains (PMDs) in some human cell lines.
Diane I, Schroeder, John D, Blair, Paul, Lott, Hung On Ken, Yu, Danna, Hong, Florence, Crary, Paul, Ashwood, Cheryl, Walker, Ian, Korf, Wendy P, Robinson, Janine M, LaSalle   +10 more
openaire   +2 more sources

Mesenchymal Stromal Cells from Fetal and Maternal Placenta Possess Key Similarities and Differences: Potential Implications for Their Applications in Regenerative Medicine

Cells, 2020
Placenta-derived mesenchymal stromal cells (MSC) have attracted more attention for their immune modulatory properties and poor immunogenicity, which makes them suitable for allogeneic transplantation.
Andrea Papait, Elsa Vertua, Marta Magatti, Sabrina Ceccariglia, Silvia De Munari, Antonietta Rosa Silini, Michal Sheleg, Racheli Ofir, Ornella Parolini   +8 more
doaj   +1 more source

Preliminary Study of Iron Concentration in the Human Placenta in Twin Pregnancies

Biomolecules, 2023
Background: Pregnancy significantly increases the demand for iron (Fe) in the female body to facilitate maternal blood volume expansion, placental development, and fetal growth. As Fe flux in pregnancy is significantly influenced by the placenta, the aim
Konrad Grzeszczak, Patrycja Kapczuk, Patrycja Kupnicka, Maciej Mularczyk, Sebastian Kwiatkowski, Dariusz Chlubek, Danuta Kosik-Bogacka   +6 more
doaj   +1 more source

Acellular Human Placenta Small-Diameter Vessels as a Favorable Source of Super-Microsurgical Vascular Replacements: A Proof of Concept

Bioengineering, 2023
In this study, we aimed to evaluate the human placenta as a source of blood vessels that can be harvested for vascular graft fabrication in the submillimeter range. Our approach included graft modification to prevent thrombotic events.
Florian Falkner, Simon Andreas Mayer, Benjamin Thomas, Sarah Onon Zimmermann, Sonja Walter, Patrick Heimel, Wilko Thiele, Jonathan Paul Sleeman, Amir Khosrow Bigdeli, Herbert Kiss, Bruno Karl Podesser, Ulrich Kneser, Helga Bergmeister, Karl Heinrich Schneider   +13 more
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Serotonin system in the human placenta – the knowns and unknowns

Frontiers in Endocrinology, 2022
The biogenic monoamine serotonin (5-hydroxytryptamine, 5-HT) is a chemical messenger widely distributed in the brain and various other organs. Its homeostasis is maintained by the coordinated activity of a variety of proteins, including enzymes of ...
Maja Perić, Ivona Bečeheli, Lipa Čičin-Šain, Gernot Desoye, Jasminka Štefulj   +4 more
doaj   +1 more source

Placental development and preeclampsia

生物医学转化, 2022
Serving as the interface between the fetal and maternal environment during gestation, the placenta plays critical roles in the protection of the developing fetus and the maintenance of pregnancy.
Zhu Yuelin, Li Qianqian, Wang Yanling, Shao Xuan   +3 more
doaj   +1 more source