Results 21 to 30 of about 229,879 (262)

Placental development and preeclampsia

生物医学转化, 2022
Serving as the interface between the fetal and maternal environment during gestation, the placenta plays critical roles in the protection of the developing fetus and the maintenance of pregnancy.
Zhu Yuelin, Li Qianqian, Wang Yanling, Shao Xuan   +3 more
doaj   +1 more source

Isolation and characterization of galectin-1 binding proteins from human placenta [PDF]

Journal of the Serbian Chemical Society, 2000
Galectin-1 binding proteins were isolated from human placenta by affinity chromatography on a column with immobilized endogenous lectin. The molecular masses of the isolated proteins of 170, 67 and 56 kDa were estimated by gel filtration and SDS-
Janković Miroslava
doaj   +3 more sources

Gestational Exposure to Cigarette Smoke Suppresses the Gasotransmitter H2S Biogenesis and the Effects Are Transmitted Transgenerationally

Frontiers in Immunology, 2020
Rationale: Gestational cigarette smoke (CS) impairs lung angiogenesis and alveolarization, promoting transgenerational development of asthma and bronchopulmonary dysplasia (BPD).
Shashi P. Singh, Dinesh Devadoss, Marko Manevski, Aryaz Sheybani, Teodora Ivanciuc, Vernat Exil, Hemant Agarwal, Veena Raizada, Roberto P. Garofalo, Hitendra S. Chand, Mohan L. Sopori   +10 more
doaj   +1 more source

The Effect of Genetic Variation on the Placental Transcriptome in Humans

Frontiers in Genetics, 2019
The knowledge of genetic variants shaping human placental transcriptome is limited and they are not cataloged in the Genotype-Tissue Expression project.
Triin Kikas, Kristiina Rull, Kristiina Rull, Kristiina Rull, Robin N. Beaumont, Rachel M. Freathy, Maris Laan   +6 more
doaj   +1 more source

Localized Expression of Histamine H1 Receptors in Syncytiotrophoblast Cells of Human Placenta

Journal of Pharmacological Sciences, 2006
The previous Northern blot analysis and in situ hybridization studies showed that histamine H1-receptor (H1R) mRNA is expressed in human placenta and suggested that H1R plays some roles in the function of placenta in pregnancy. To investigate further, it
Kazuto Matsuyama, Tatsuya Ichikawa, Yuichi Nitta, Yoshio Ikoma, Kazutaka Ishimura, Shuhei Horio, Hiroyuki Fukui   +6 more
doaj   +1 more source

A genome-wide comparison of mesenchymal stem cells derived from human placenta and umbilical cord

Taiwanese Journal of Obstetrics & Gynecology, 2017
Objective: The human umbilical cord and placenta have been considered as attractive alternative sources for noninvasive isolation of human mesenchymal stem cells (hMSCs).
Sen-Wen Teng, Yu-Shu Lo, Wei-Ting Liu, Yogi Hsuan, Willie Lin   +4 more
doaj   +1 more source

Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA Sequencing

Cells, 2022
Background: The placenta is an important organ for fetal and maternal health during pregnancy and impacts offspring health late in life. Defects in placental vasculature and trophoblast have been identified in several pregnancy complications.
Han Li, Hao Peng, Wei Hong, Yingying Wei, Haojun Tian, Xiaojie Huang, Linyan Jia, Jing Zheng, Tao Duan, Qizhi He, Kai Wang   +10 more
doaj   +1 more source

Syncytial Knots, Sprouts, Apoptosis, and Trophoblast Deportation from the Human Placenta

Taiwanese Journal of Obstetrics & Gynecology, 2009
The syncytiotrophoblast (STB) that forms the epithelial covering of the placental villous tree has a unique cell biology on account of its syncytial nature.
Graham J. Burton, Carolyn J.P. Jones
doaj   +1 more source

Genomic imprinting in human placentation

Reproductive Medicine and Biology, 2022
Background Genomic imprinting (GI) is a mammalian‐specific epigenetic phenomenon that has been implicated in the evolution of the placenta in mammals.
Eri H. Kobayashi, Shun Shibata, Akira Oike, Norio Kobayashi, Hirotaka Hamada, Hiroaki Okae, Takahiro Arima   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source