Results 71 to 80 of about 8,929,794 (358)
Lack of detection of a human placenta microbiome in samples from preterm and term deliveries
Microbiome, 2018 Historically, the human womb has been thought to be sterile in healthy pregnancies, but this idea has been challenged by recent studies using DNA sequence-based methods, which have suggested that the womb is colonized with bacteria. For example, analysis
Jacob S. Leiby +13 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Syncytial Knots, Sprouts, Apoptosis, and Trophoblast Deportation from the Human Placenta
Taiwanese Journal of Obstetrics & Gynecology, 2009 The syncytiotrophoblast (STB) that forms the epithelial covering of the placental villous tree has a unique cell biology on account of its syncytial nature.
Graham J. Burton, Carolyn J.P. Jones
doaj +1 more source
Modeling the human placental barrier to understand Toxoplasma gondii´s vertical transmission
Frontiers in Cellular and Infection Microbiology, 2023 Toxoplasma gondii is a ubiquitous apicomplexan parasite that can infect virtually any warm-blooded animal. Acquired infection during pregnancy and the placental breach, is at the core of the most devastating consequences of toxoplasmosis. T.
Paula Faral-Tello +4 more
doaj +1 more source
Isolation and characterization of a light chain variable region gene for human rheumatoid factors. [PDF]
, 1987 Previously, we isolated a Vk gene (Humkv325) from a human placenta that encodes RF light chains bearing the PSL2 and PSL3 CRI markers. Here we report the isolation and characterization of a second human Vk gene (Humkv328) that can be used for RF ...
Carson, DA +4 more
core
Differential expression of microRNA-206 and its target genes in pre-eclampsia [PDF]
, 2015 Objectives: Pre-eclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify novel circulating miRNAs in maternal plasma that may be ...
Akehurst, Christine +12 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa +7 more
wiley +1 more source
Lactic Acid Transport Mediated by Aquaporin-9: Implications on the Pathophysiology of Preeclampsia
Frontiers in Physiology, 2021 Aquaporin-9 (AQP9) expression is significantly increased in preeclamptic placentas. Since feto-maternal water transfer is not altered in preeclampsia, the main role of AQP9 in human placenta is unclear.
Yollyseth Medina +7 more
doaj +1 more source
cDNA and Gene Analyses Imply a Novel Structure for a Rat Carcinoembryonic Antigen-related Protein [PDF]
, 1990 The gene encoding the human tumor marker carcinoembryonic antigen (CEA) belongs to a gene family which can be subdivided into the CEA and the pregnancy-specific glycoprotein subgroups.
Lucas, Kurt +3 more
core
A lesson for cancer research : placental microarray gene analysis in preeclampsia [PDF]
, 2012 Tumor progression and pregnancy share many common features, such as immune tolerance and invasion. The invasion of trophoblasts in the placenta into the uterine wall is essential for fetal development, and is thus precisely regulated.
Louwen, Frank +4 more
core +2 more sources