Association of the human platelet antigens polymorphisms with platelet count in patients with COVID-19 [PDF]
Polymorphism in human platelet antigen (HPA)-1 and HPA-3 (GPIIb/IIIa), HPA-2 (GPIb/IX), HPA-4 (GPIIIa), HPA-5 (GPIa/IIa), & HPA-15 (CD109) was investigated in 86 COVID-19-infected patients with thrombocytopenia (Group A) and 136 COVID-19-infected ...
Kazem Ghaffari +9 more
doaj +4 more sources
Platelet-independent methods for detecting antibodies to human platelet antigens. [PDF]
Dear Sir, I read with great interest the review paper entitled “Advances in alloimmune thrombocytopenia: perspectives on current concepts of human platelet antigens, antibody detection strategies, and genotyping” by Hayashi T et al., which was published recently in Blood Transfusion1.
Skaik Y.
europepmc +4 more sources
Molecular typing of human platelet antigens in immune thrombocytopenia patients in northern Brazil [PDF]
Background: Immune thrombocytopenia is an immune disease characterized by thrombocytopenia and bleeding due to platelet antibodies against platelet membrane glycoproteins. Human platelet antigens are derived from polymorphisms of these glycoproteins. The
Julia Cavalcante do Carmo +6 more
doaj +3 more sources
Frequency of human platelet antigens −1 to −5 and −15 in Turkmen blood donors [PDF]
Background: Due to the presence of platelet antigen polymorphisms, human platelet membrane glycoproteins can be identified as an alloantigen or autoantigen.
Maedeh Nozarimirarkolaei +5 more
doaj +3 more sources
Human platelet antigens and primary immune thrombocytopenia [PDF]
Vagner Castro
doaj +4 more sources
Factor XI antigen and activity in human platelets [PDF]
Abstract Washed platelets, contaminated with less than 0.20% plasma factor XI, were examined for the presence of factor XI antigen and activity. These platelets contained a factor-XI-like coagulant activity (0.67 +/- 0.11 U/10(11) platelets) that remained constant after successive washes.
Tuszynski Gp +4 more
openalex +4 more sources
Human platelet antigen-3 polymorphism as a risk factor for rheumatological manifestations in hepatitis C [PDF]
INTRODUCTION: Hepatitis C virus (HCV) infection is involved in the pathogenesis of autoimmune and rheumatic disorders. Although the human platelet antigens (HPA) polymorphism are associated with HCV persistence, they have not been investigated in ...
Natália Bronzatto Medolago +6 more
doaj +2 more sources
Association of human platelet antigen polymorphisms with platelet count and mean platelet volume [PDF]
Although recent genome-wide association studies have identified a number of single nucleotide polymorphisms associated with platelet count and mean platelet volume (MPV), it is unclear whether polymorphisms in the human platelet antigens (HPA) genes are associated with platelet count and MPV.
Shihang Zhou +5 more
openalex +3 more sources
Generation of human antibodies targeting human platelet antigen (
AbstractBackgroundFetal and neonatal alloimmune thrombocytopenia (FNAIT) is a condition during pregnancy, which can lead to thrombocytopenia and a bleeding tendency with intracranial hemorrhage (ICH) being the most concerning complication in the fetus or neonate.
Janita J. Oosterhoff +9 more
openalex +5 more sources
Effect of Freeze-Dried Porcine Platelet Lysate on Wound Healing in Rats [PDF]
Background and Objectives: Complications in wound healing present significant challenges in clinical settings. While platelet-rich plasma from human sources has been extensively used to aid wound recovery, allogeneic or xenogeneic platelet-derived ...
Winson Min-Teng Low +6 more
doaj +2 more sources

