Molecular typing of human platelet antigens in immune thrombocytopenia patients in northern Brazil. [PDF]
Background: Immune thrombocytopenia is an immune disease characterized by thrombocytopenia and bleeding due to platelet antibodies against platelet membrane glycoproteins. Human platelet antigens are derived from polymorphisms of these glycoproteins. The
Carmo JCD +6 more
europepmc +2 more sources
Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S. +3 more
core +4 more sources
Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture [PDF]
Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric oxide synthase
Damian J Murphy +17 more
core +1 more source
PLATELET STUDIES INVOLVING THE STABILIZATION OF PLATELET MEMBRANES: APPLICATION TO RECEPTORS, ANTIGENS AND MEMBRANE ...
JOHN ALLEN. MAPLES (7976576)
core +3 more sources
Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 [PDF]
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by 2-dimensional gel electrophoresis were probed with pooled sera from ...
Midzi, N. +28 more
core +1 more source
Platelet adhesion in atherogenesis [PDF]
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyPlatelets are known to play a key role in acute coronary events, such as myocardial infarction, associated with advanced
Watkins, Jennifer
core +3 more sources
Studies on in vitro human T cell reactivity to antigens of mycobacterium tuberculosis [PDF]
Studies on Mycobacterium tuberculosis (MTB) antigens are important to improve immunodiagnostics and vaccine efficacy. A novel genome based strategy for antigen discovery is to relate what is highly expressed by bacilli in vivo or in vitro, to what is ...
Gideon, Hannah Priyadarshini
core +1 more source
Localization of platelet antigens in human kidney disease
The localization of a platelet antigen or antigens kidneys from 106 patients with renal disease was evaluated with immunofluorescent microscopy by using a rabbit antibody to human platelets. The antiplatelet IgG fixed to the surface membrane of platelets did not react with erythrocytes, leukocytes, plasma, normal kidney, or a variety of normal tissue ...
Miller, Kenneth +2 more
openaire +2 more sources
Comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections [PDF]
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid – SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories.
Dawson, E. +50 more
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

