Platelet-independent methods for detecting antibodies to human platelet antigens. [PDF]
Dear Sir, I read with great interest the review paper entitled “Advances in alloimmune thrombocytopenia: perspectives on current concepts of human platelet antigens, antibody detection strategies, and genotyping” by Hayashi T et al., which was published recently in Blood Transfusion1.
Skaik Y.
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Human platelet antigens and primary immune thrombocytopenia. [PDF]
Castro V.
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Human platelet antigens – 2013 [PDF]
To date, 33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been implicated in alloimmune platelet disorders including foetal and neonatal alloimmune thrombocytopenia (FNAIT), posttransfusion purpura (PTP) and multitransfusion platelet refractoriness (MPR). The greatest
B R, Curtis, J G, McFarland
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The origin of ABH antigens on human platelets [PDF]
Abstract ABH antigens are present on platelets from individuals of the corresponding red cell phenotype, but the extent to which these antigens are intrinsic or adsorbed remains undefined. To evaluate platelets for intrinsic H substance, an IgM mouse monoclonal antibody against type 2H chain (the intrinsic H structure found on ...
R A, Dunstan +3 more
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Human Platelet Antigen Genotyping and Expression of CD109 (Human Platelet Antigen 15) mRNA in Various Human Cell Types [PDF]
CD109 gene encodes a glycosylphosphatidylinositol-linked glycoprotein found in a subset of platelets and endothelial cell, and human platelet antigen (HPA) 15 is found on CD109. We evaluated the HPA genotype and/or the CD109 mRNA expression on two peripheral blood stem cells (PBSC), two peripheral bloods (PB), 12 granulocyte products, natural killer ...
Hwang, Sang Mee +8 more
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Determination of platelet antigens and glycoproteins in the human fetus [PDF]
The autosomal recessive transmission of Glanzmann's thrombasthenia (GT) and Bernard-Soulier syndrome (BSS), together with requests of families who already had children with these diseases, prompted us to investigate the feasibility of their antenatal diagnosis. The preliminary step leading to the early detection of GT or BSS was to characterize, in the
Y, Gruel +5 more
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Factor XI antigen and activity in human platelets [PDF]
Abstract Washed platelets, contaminated with less than 0.20% plasma factor XI, were examined for the presence of factor XI antigen and activity. These platelets contained a factor-XI-like coagulant activity (0.67 +/- 0.11 U/10(11) platelets) that remained constant after successive washes.
G P, Tuszynski +4 more
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Association of human platelet antigen polymorphisms with platelet count and mean platelet volume [PDF]
Although recent genome-wide association studies have identified a number of single nucleotide polymorphisms associated with platelet count and mean platelet volume (MPV), it is unclear whether polymorphisms in the human platelet antigens (HPA) genes are associated with platelet count and MPV.
Shihang, Zhou +5 more
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Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors [PDF]
To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.We included 867 healthy unrelated volunteer donors who donated platelets between January 2011 and December 2014.
Dutra, Valeria de Freitas +6 more
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Immunocytochemical Studies on Platelets. The Demonstration of a Common Antigen in Human Platelets and Megakaryocytes [PDF]
Abstract By means of the fluorescent antibody technic of Coons and Kaplan it was possible to demonstrate a common antigenic structure in human platelets and megakaryocytes, both in nonthrombocytopenic cases and in cases with idiopathic thrombocytopenic purpura.
J J, VAZQUEZ, J H, LEWIS
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