Results 21 to 30 of about 53,997 (201)

Foetal and neonatal alloimune thrombocytopenia as a rare exapmle of thrombocytopenia in newborn

Journal of Education, Health and Sport, 2018
Foetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by antigenic incompatibility of platelets between a pregnant woman and her child, resulting in producing antibodies by a mother against specific antigens (HPA- Human Platelet Antigens ...
Maciej Kamiński, Paulina Grzesik, Monika Długoń, Maciej Majsterek, Żaneta Kimber-Trojnar, Krzysztof Kamiński, Bożena Leszczyńska-Gorzelak   +6 more
doaj   +3 more sources

Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report

Forbes Tıp Dergisi, 2021
Neonatal Alloimmune Thrombocytopenia (NAIT), a complication of maternal alloimmunization against fetal platelets, is the result of immune destruction of platelets due to maternal antibodies in the early period.
Gökhan Kaya, Sema Tanriverdi
doaj   +1 more source

Human platelet antigen allelic diversity in Peninsular Malaysia [PDF]

Immunohematology, 2016
Abstract Human platelet antigens (HPAs) are polymorphic and immunogenic glycoproteins encoded by biallelic genes on human chromosome 17 (HPA-1 to -4 and HPA-6 to -11), chromosome 5 (HPA-5), and chromosome 6 (HPA-15) and expressed on the surface of platelets. In the present study, we typed seven HPA loci (HPA-1 to -
Wan Ubaidillah W, Syafawati, Zulkafli, Zefarina, Zafarina, Zafarina, Mohd Nazri, Hassan, Mohd Nor, Norazmi, Sundararajulu, Panneerchelvam, Geoffrey K, Chambers, Hisham Atan, Edinur   +7 more
openaire   +2 more sources

Platelet antibodies identification: comparison between two laboratory tests

Hematology, Transfusion and Cell Therapy, 2022
Introduction: Platelet antibody identification is indispensable for diagnosing the human platelet antigen (HPA) or human leukocyte antigen (HLA) immunization, mostly because it can restrict the compatibility and results of transfusions. Correct detection
Valeria de Freitas Dutra, Thiago Henrique Costa, Leandro Dinalli Santos, Marilia Fernandes Mascarenhas Sirianni, Maria Giselda Aravechia, José Mauro Kutner, Carolina Bonet Bub   +6 more
doaj   +1 more source

Unappreciated HLA Antibodies in Adult Immune Thrombocytopenic Purpura

Journal of the Formosan Medical Association, 2007
Immune thrombocytopenic purpura (ITP) is an autoimmune disease. Platelet refractoriness is frequently seen in patients with ITP. Platelets express platelet-specific antigens and human leukocyte antigens (HLA).
Jeong-Shi Lin, Jau-Yi Lyou, Ying-Ju Chen, Pei-Shan Chen, Hsueng-Mei Liu, Chao-Hung Ho, Tsung-Chi Hao, Cheng-Hwai Tzeng   +7 more
doaj   +1 more source

Microfluidic approach to genotyping human platelet antigens

IET Nanobiotechnology, 2012
Centralised laboratories routinely determine blood types by serological and molecular methods. Current practices have limitations in terms of cost, time and accessibility. Miniaturised microfluidic platforms offer an alternative to conventional genotyping methods, since they consume fewer reagents, provide faster analysis and allow for complete ...
C, Lim, D P, Manage, A, Atrazhev, G, Denomme, C J, Backhouse, J P, Acker   +5 more
openaire   +2 more sources

The origin of ABH antigens on human platelets [PDF]

Blood, 1985
Abstract ABH antigens are present on platelets from individuals of the corresponding red cell phenotype, but the extent to which these antigens are intrinsic or adsorbed remains undefined. To evaluate platelets for intrinsic H substance, an IgM mouse monoclonal antibody against type 2H chain (the intrinsic H structure found on ...
R A, Dunstan, M B, Simpson, R W, Knowles, W F, Rosse   +3 more
openaire   +3 more sources

A case report of neonatal alloimmune thrombocytopenia: The utility of platelet crossmatch studies in the diagnosis and management

Global Journal of Transfusion Medicine, 2019
Alloimmune thrombocytopenia is the most common cause of severe thrombocytopenia and intracranial bleed in the perinatal period, resulting from placental transfer of maternal platelet antibodies directed against the paternal-derived fetal platelet ...
H A Venkatesh, Abhishek Paul, Ambuja Kantharaj, Shivaram Chandrashekar   +3 more
doaj   +1 more source

Influence of platelet antigens differences between donor and recipient on neutropenia and thrombocytopenia duration after allogeneic stem cell transplantation

Онкогематология, 2022
Purpose: to study influence of platelet antigens system (HPA — Human Platelet Antigens) differences between donor and recipient on neutropenia and trombocytopenia duration after hematopoietic stem cells transplantation (HSCT).Materials and methods: 40 ...
L. L. Golovkina, R. M. Kutyina
doaj   +1 more source

Platelet antibody detection assays: a single-laboratory comparison of MAIPA, PIFT, and microsphere-based multiplex assays Pak-Lx

Hematology, Transfusion and Cell Therapy
Background and Objectives: The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet refractoriness ...
Thiago Henrique Costa, Carolina Bonet-Bub, José Mauro Kutner   +2 more
doaj   +1 more source