Results 31 to 40 of about 53,997 (201)

A case report of neonatal alloimmune thrombocytopenic purpura: the importance of correct diagnosis for future pregnancies

open access: yesSão Paulo Medical Journal
CONTEXT: Neonatal alloimmune thrombocytopenic purpura (NAITP) is a neonatal disorder characterized by maternal alloimmunization against fetal platelet antigens inherited from the father.
Rita Fontão-Wendel   +5 more
doaj   +1 more source

The absence of the human platelet antigen polymorphism effect on fibrosis progression in human immunodeficiency virus-1/hepatitis C virus coinfected patients

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2015
INTRODUCTION:Hepatic fibrosis progression in patients with chronic hepatitis C virus infections has been associated with viral and host factors, including genetic polymorphisms.
Natália Picelli   +7 more
doaj   +1 more source

Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages

open access: yesPlatelets, 2023
Immune-mediated platelet refractoriness (PR) remains a significant problem in the setting of platelet transfusion and is predominantly caused by the presence of alloantibodies directed against class I human leukocyte antigens (HLA). Opsonization of donor
Thijs L. J. van Osch   +11 more
doaj   +1 more source

Human platelet antigen polymorphisms and the risk of chronic Chagas disease cardiomyopathy

open access: yesPlatelets, 2020
Human platelet antigen (HPA) polymorphisms are considered to be a risk factor for cardiac and vascular diseases, but the role of HPA in chronic Chagas disease cardiomyopathy (CCC) is not available.
Deborah Elzita do Carmo Corrêa   +8 more
doaj   +1 more source

Anti-HPA-1b Mediated Posttransfusion Purpura: A Case Report

open access: yesCase Reports in Medicine, 2013
Posttransfusion purpura (PTP) is an uncommon, but potentially fatal, transfusion reaction characterized by profound thrombocytopenia and bleeding. PTP is caused by alloimmunization to human platelet specific antigens following blood component transfusion.
O. P. Arewa, S. Nahirniak, G. Clarke
doaj   +1 more source

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors

open access: yesEinstein (São Paulo)
Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Valeria de Freitas Dutra   +6 more
doaj   +1 more source

Localization of platelet antigens in human kidney disease

open access: yesKidney International, 1980
The localization of a platelet antigen or antigens kidneys from 106 patients with renal disease was evaluated with immunofluorescent microscopy by using a rabbit antibody to human platelets. The antiplatelet IgG fixed to the surface membrane of platelets did not react with erythrocytes, leukocytes, plasma, normal kidney, or a variety of normal tissue ...
Miller, Kenneth   +2 more
openaire   +2 more sources

Transfusion medicine and molecular genetic methods

open access: yesInternational Journal of Preventive Medicine, 2018
Transfusion procedures are always complicated by potential genetic mismatching between donor and recipient. Compatibility is determined by several major antigens, such as the ABO and Rhesus blood groups. Matching for other blood groups (Kell, Kidd, Duffy,
Rozieyati Mohamed Saleh   +4 more
doaj   +1 more source

Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis

open access: yesFrontiers in Immunology, 2019
Psoriasis is a frequent systemic inflammatory autoimmune disease characterized primarily by skin lesions with massive infiltration of leukocytes, but frequently also presents with cardiovascular comorbidities.
Franziska Herster   +18 more
doaj   +1 more source

Platelet Toll-Like-Receptor-2 and -4 Mediate Different Immune-Related Responses to Bacterial Ligands

open access: yesTH Open, 2022
Background Like immune cells, platelets express toll-like receptors (TLRs) on their surface membrane. TLR2 and TLR4 are able to recognize bacterial antigens and have the potential to influence hemostatic functions and classical intracellular signaling ...
Marius Niklaus   +7 more
doaj   +1 more source

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