Results 41 to 50 of about 53,997 (201)

Diagnosis of Neonatal Alloimmune Thrombocytopenia: Determination of the Specificity of Antiplatelet Alloantibodies in the Maternal Blood Plasma Using a Molecular and Genetic Method

Инновационная медицина Кубани, 2023
Background: Thrombocytopenia occurs in 1-5 % of newborns (platelet count < 150 × 109/L). Low platelet count of 50 × 109/L leads to the hemorrhagic syndrome, with one of its causes being neonatal alloimmune thrombocytopenia resulting from ...
N. V. Mineeva, S. V. Gavrovskaya, E. A. Sysoeva, S. V. Sidorkevich   +3 more
doaj   +1 more source

PLT antigen discrepancy pattern among couples with recurrent abortion

Frontiers in Medicine
BackgroundRecurrent abortion refers to a condition of two or more consecutive pregnancies without known etiology affected by miscarriage before the completion of the 20th week of gestational age.
Ghazal Ahmadzadeh Shad, Ali Ghasemi, Maryam Zadsar, Mojgan Shaeigan, Shahram Samiee, Ahad Zare   +5 more
doaj   +1 more source

Applicability of an instrument to identify human leukocyte antigen-compatible donors for platelet transfusions

Hematology, Transfusion and Cell Therapy, 2018
Background: The selection of compatible human leukocyte antigen platelets has been associated with improved platelet increments. Therefore, an effective strategy would be the selection of donors who are genetically compatible according to the human ...
Millena Gomes Ferreira, Fernanda Bernadelli De Vito, Aline Aparecida Ferreira, Carolina Bonet Bub, Fernando Antônio Vinhal dos Santos, Adilson Botelho Filho, Sheila Soares Silva, Helio Moraes-Souza   +7 more
doaj   +1 more source

Severe intracranial haemorrhage in neonatal alloimmune thrombocytopenia due to antibodies against human platelet antigen 1b: Case report and literature review [PDF]

, 2022
Gordana Tomac, Koraljka Gojčeta, Ruža Grizelj, Désirée Coen Herak, Sanja Baršić Ostojić, Branka Golubić Ćepulić   +5 more
openalex   +1 more source

Human platelet‐specific antigens frequencies in the Argentinean population [PDF]

Transfusion Medicine, 2008
summary The frequencies of several human platelet antigens (HPAs) vary between different populations and are a major determinant for the prevalence of HPA alloimmunization and its clinical associated entities. The aim of this study was to characterize the allele frequencies of seven HPA systems in two different ethnic groups from the Argentinean city ...
C D, De La Vega Elena, N, Nogués, A, Fernández Montoya, S, Chialina, P D, Blanzaco, E, Theiller, M A, Raillon, N, Arancegui, E, Solis, S, Oyonarte, V, Crespo Ferrer, A, Campos Muñoz, E, Muñiz-Díaz   +12 more
openaire   +2 more sources

Determination of an unrelated donor pool size for human leukocyte antigen-matched platelets in Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2016
Background: Successful transfusion of platelet refractory patients is a challenge. Many potential donors are needed to sustain human leukocyte antigen matched-platelet transfusion programs because of the different types of antigens and the constant needs
Carolina Bonet Bub, Margareth Afonso Torres, Maria Elisa Moraes, Nelson Hamerschlak, José Mauro Kutner   +4 more
doaj   +1 more source

Allele frequencies of Human Platelet Antigen 1 and Human Platelet Antigen 5 in the Maltese

, 2021
Background: The human platelet antigen systems consist of antigenic polymorphisms that arise from single base pair substitutions leading to amino acid changes in platelet glycoproteins. These polymorphisms cause a variety of clinically significant conditions where platelet typing is essential for accurate diagnosis and subsequent treatment.
Falzon Lia, Martina, Samut Tagliaferro, Sarah, Farrugia, Rosienne   +2 more
openaire   +1 more source

Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke

Stem Cells International, 2016
Currently, there is increasing interest in human bone marrow stromal cells (hBMSCs) as regeneration therapy against cerebral stroke. The aim of the present study was to evaluate the feasibility and validity of hBMSC cultures with allogeneic platelet ...
Chengbo Tan, Hideo Shichinohe, Zifeng Wang, Shuji Hamauchi, Takeo Abumiya, Naoki Nakayama, Ken Kazumata, Tsuneo Ito, Kohsuke Kudo, Shigeru Takamoto, Kiyohiro Houkin   +10 more
doaj   +1 more source

Genetic restriction of humoral immune response

Онкогематология, 2014
The review provides information about immune response initiation against foreign agents. Significance of separate molecules of major histocompatibility complex in antibodies formation after blood transfusion, during pregnancy, after organ transplantation
L. L. Golovkina
doaj   +3 more sources

Pyelolithotomy in a patient with Glanzmann thrombasthenia and antiglycoprotein IIb/IIIa antibodies: the shortest possible duration of treatment with recombinant activated factor VII and platelet transfusions

The Turkish Journal of Pediatrics, 2003
Transfusion of platelet concentrates remains the first-line therapy for Glanzmann thrombasthenia in case of bleeding or preparation for surgery. However, development of antibodies to platelet glycoprotein (Gp) IIb/IIIa complex or human leukocyte ...
Omer Devecioğlu, Ayşegül Unüvar, Sema Anak, Ilmay Bilge, Haluk Ander, Orhan Ziylan   +5 more
doaj