Results 121 to 130 of about 5,283,554 (314)
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Human Potentials Management in Transport
The paper explores the significance of human potentials management in micro and macro transport systems and investigates to what extent do the human potentials represent the factor of growth and development of transport systems. The facts gathered in this paper should represent the quantitative starting points for viewing the specifics of transport ...
Pupavac, Drago +2 more
openaire +3 more sources
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Potential use of mesenchymal stem cells in human meniscal repair: current insights
Jaewoo Pak,1–3* Jung Hun Lee,1,4* Kwang Seung Park,4 Jeong Ho Jeon,4 Sang Hee Lee4 1Stems Medical Clinic, Gangnamgu, Seoul, Republic of Korea; 2TEDA‑Puhua International Hospital, Tianjin, People’s Republic of China; 3Life Science Institute ...
Pak J, Jeon JH, Lee SH, Park KS, Lee JH
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Artificial intelligence governance in international relations: a human rights perspective [PDF]
openAdvancements in artificial intelligence (AI) technology are rapidly transforming global governance structures and institutions, including key bodies responsible for promoting and protecting human rights and putting AI as one of the key topics on the ...
STANISAVLJEVIC, KATARINA
core
Maximising women's potential in the UK's retail sector
Purpose – A defining characteristic of the UK retail sector is the high number of women it employs but there remains an enduring under-representation of women in its management positions.
Whysall, P +9 more
core +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Projecting scenarios for the spread of emerging infectious diseases (EID) well before a possible next “Disease X” pandemic has become a challenge of utmost importance and urgency.
Lorenzo Mari +2 more
core
While migration has been an inflammatory issue for society for centuries, the 21st century has catapulted the issue into the realm of terrorism and radicalisation threats. The narratives around migration have been particularly used as a manipulative tool
Brady, E.
core

