Results 31 to 40 of about 5,283,554 (314)

Exploring multi-omics and clinical characteristics linked to accelerated biological aging in Asian women of reproductive age: insights from the S-PRESTO study

Genome Medicine
Background Phenotypic age (PhenoAge), a widely used marker of biological aging, has been shown to be a robust predictor of all-cause mortality and morbidity in different populations.
Li Chen, Karen Mei-Ling Tan, Jia Xu, Priti Mishra, Sartaj Ahmad Mir, Min Gong, Kothandaraman Narasimhan, Bryan Ng, Jun Shi Lai, Mya Thway Tint, Shirong Cai, Suresh Anand Sadananthan, Navin Michael, Jadegoud Yaligar, Sambasivam Sendhil Velan, Melvin Khee Shing Leow, Kok Hian Tan, Jerry Chan, Michael J. Meaney, Shiao-Yng Chan, Yap Seng Chong, Johan G. Eriksson   +21 more
doaj   +1 more source

Delay discounting is associated with addiction and mental health measures while controlling for health behaviors and health barriers in a large US sample

Addictive Behaviors Reports
Background: Excessive discounting of future rewards [delay discounting (DD)] may be a transdiagnostic process and treatment target underlying behavioral health outcomes, including trauma, depression, anxiety, and problematic substance use.
Jeremiah M. Brown, Michael Sofis, Sara Zimmer, Brent A. Kaplan   +3 more
doaj   +1 more source

What Is the Efficacy of the Autoimmune Protocol (AIP) Diet in People with Rheumatoid Arthritis? A Mixed-Methods Pilot Intervention Study

Medical Sciences Forum, 2023
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterised by inflammation of the synovial lining of joints, causing pain, swelling, and stiffness with potential for joint deformity. RA affects about 2.3% of New Zealanders and 2.8% of Māori.
Julianne McNeill, Caryn Zinn, Gael Mearns, Rebecca Grainger   +3 more
doaj   +1 more source

The chlorinating potential of the human monocyte [PDF]

Blood, 1983
Abstract Human monocytes incubated with phorbol myristate acetate (PMA) or opsonized zymosan particles can chlorinate the beta-amino acid taurine to its monochloramine derivative. Taurine monochloramine can then be quantitated by its ability to oxidize 5-thio-2-nitrobenzoic acid to its disulfide or by its characteristic absorption peak ...
M B, Lampert, S J, Weiss
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Developing human capital in Africa: carving a role for human resource professionals and practitioners

, 2018
Africa is a continent with remarkable economic potential yet the least developed largely due to its inadequate human capital to transform this potential into social and economic development.
Agbebi, Motolani, Hamza B. Zakaria, Agbedi, Motolani, Ken Kamoche, Zakaria, Hamza B., Mamman, Aminu, Kamoche, Ken, Motolani Agbebi, Aminu Mamman   +8 more
core   +1 more source

Being barefoot. Prevalence at home, in school and during sport: a cross-sectional survey of 714 New Zealand secondary school boys

Journal of Foot and Ankle Research, 2018
Background It may be assumed that a combination of culture, climate and economic resource are the major reasons that non-industrialised countries have a higher prevalence of barefoot activity.
Peter Francis, Grant Schofield, Lisa Mackay   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Investigation of potential respiratory adverse effects of micro/nanofibrillated cellulose and cellulose nanocrystals using human lung cell lines. [PDF]

, 2022
publicado em: Environ Mol Mutagen. 2022 Aug;63(Suppl 1):72-73. (Abstracts from the 13th International Conference on Environmental Mutagens and 53rd Annual Meeting of the Environmental Mutagenesis and Genomics Society). https://onlinelibrary.wiley.com/toc/
Pinto, Fátima, Vital, Nádia, Pereira, Joana F.S., Vieira, Luís, Silva, Maria João, Fernandes, Susete N., Ventura, Célia, Jordan, Peter, Pedrosa, Jorge F.S., Lourenço, Ana Filipa, Bettencourt, Ana, Silva, Catarina C., Cadete, João, Gonçalves, Lídia, Louro, Henriqueta, Matos, Paulo, Godinho, Maria Helena, Ferreira, Paulo J.T.   +17 more
core