Results 111 to 120 of about 1,491,738 (312)
PECULIARITIES OF REGIONAL NATURE MANAGEMENT IN PAVLODAR REGION
The paper studies the territory of the Middle Irtysh within Pavlodar region in which there is an exacerbation of geoecological situation. The author analyzed the peculiarities of nature management in one of the major industrial regions of Northern ...
S. Sh.-A. Smailov
doaj
Although the global population continues to grow, the coming decades will witness the most rapid expansion of urban population in human history, primarily, driven by large-scale rural-to-urban migration.
Qing LUO +11 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
European Society of Hypertension Practice Guidelines for home blood pressure monitoring
Self-monitoring of blood pressure by patients at home (home blood pressure monitoring (HBPM)) is being increasingly used in many countries and is well accepted by hypertensive patients.
G S Stergiou +72 more
core +2 more sources
To better guide conservation policies, it is crucial to understand the mechanisms responsible for biodiversity loss. Maps illustrating anthropogenic pressures on biodiversity represent a rapidly developing technical solution to address this issue.
Paul Rouveyrol
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Species richness response to human pressure hides important assemblage transformations. [PDF]
Cazalis V.
europepmc +1 more source
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The pressure gradient in the human respiratory tract
Respiratory airways cause resistance to air flow during inhalation and exhalation. The pressure gradient is necessary to transport the air from the mount (or nose) to pulmonary alveoli. The knowledge of pressure gradient (i.e.
Chovancová Michaela, Elcner Jakub
doaj +1 more source
Global protected-area coverage and human pressure on tidal flats. [PDF]
Hill NK +4 more
europepmc +1 more source

