Results 41 to 50 of about 1,491,738 (312)
Cybergeo, 2000 The peripheral Syrian desert steppe is an ecologically sensitive region like all desert margins. The objective of the program is to understand the respective influence of natural and human processes on its evolution with the use of satellite imagery and ...
F. Debaine
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Geological Heritage of the Anthropocene Epoch—A Conceptual Viewpoint
Heritage, 2019 The growth of interest in the Anthropocene has coincided with the rise of geoheritage research and these ideas seem to be mutually enriching. However, very few previous investigations were devoted to the Anthropocene geoheritage. The conceptual treatment
Dmitry A. Ruban
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Use of land located within Eselnita drainage basin [PDF]
Cinq Continents, 2011 Developed on the south-eastern side of Almãjului Mountains, Eşelniţa drainage basin neighbours upon the following basins: upon S – SV with Mala, upon SV - V with Mraconia, upon V - NV with Berzasca, upon NV - NNE with Nera and on the NNE – SE ...
DANIELA VLAD
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Environmental Research Letters, 2020 Human population growth has increased the demand for water and clean energy, leading to the massive construction of reservoirs. Reservoirs can emit greenhouse gases (GHG) affecting the atmospheric radiative budget. The radiative forcing due to CO _2 , CH
Elizabeth León-Palmero +2 more
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