Results 61 to 70 of about 1,491,738 (312)

Urgent Conservation Actions Are Needed for Qinling Lenok Brachymystax lenok tsinlingensis Li, 1966: Enlightenment From Model Simulations

Ecology and Evolution
The Qinling lenok Brachymystax lenok tsinlingensis Li, 1966, an endemic to China and South Korea, is a rare protected species. Its unique requirements to habitat have made this fish extraordinarily fragile when faced with human pressures and global ...
Yuebing Zhou, Xianghong Dong, Tao Ju, Lei Gan, Zhenlu Wang, Yuxi Lian, Peng Zhang, Xiongfeng Bai, Qing Liu, Shuhai Zhang, Jiyuan Liu, Tao Xiang, Lei Shi, Haibo Jiang, Jian Shao, Miao An   +15 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Numerical Simulation Analysis on Human Pressure During the Accident of Burying People in the Grain Silo Based on DEM

Liang you shipin ke-ji
The analysis of human force conditions in grain silo burial accidents is of great significance for emergency rescue and the development of protective devices.
HE Xiao-wei, CUI Peng-cheng, ZHANG Tao, CHEN Xin   +3 more
doaj   +1 more source

HUMAN PRESSURE AND DAMAGE TO LANDSCAPE

Sustainable Mediterranean Construction
For introducing the subject of human pressure on landscape damages, the paper deals with various issues resulting in a specific path towards the demonstration of an idea: that beauty, sustainability and respect for anthropic as well as natural milieu could provide improvement to landscape quality.
openaire   +2 more sources

The Human Pressure is Extreme'

, 1995
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Pressure–Diameter Relationship in Human Coronary Arteries [PDF]

Circulation: Cardiovascular Interventions, 2012
Background— To quantify the changes in arterial dimensions after the acute changes in pressure associated with percutaneous coronary intervention (PCI). Methods and Results— Forty-eight patients with one angiographically moderate-to-severe stenosis were included in ...
Muller O, Pyxaras SA, Trana C, Mangiacapra F, BARBATO, EMANUELE, Wijns W, Taylor CA, De Bruyne B.   +7 more
openaire   +4 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source