Results 51 to 60 of about 1,491,738 (312)

The association of disproportionately enlarged subarachnoid space hydrocephalus with cognitive deficit in a general population: the Ohasama study

open access: yesScientific Reports, 2021
Disproportionately enlarged subarachnoid space hydrocephalus (DESH) is the characteristic feature of idiopathic normal pressure hydrocephalus. We aimed to characterize the prevalence, development, and association of DESH to cognitive deficit in a large ...
Tomofumi Nishikawa   +13 more
doaj   +1 more source

Effectiveness of Medication, Surgery, and Combination Therapy to Decrease Intraocular Pressure on Glaucoma Outpatient at Outpatient Ophthalmic Clinic Dr. Soetomo General Hospital Surabaya in January – December 2017

open access: yesJuxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2022
Highlights: 1. Combination of medication and surgery on glaucoma had the least post-therapy intraocular pressure. 2. There was no significant difference in the efficacy of drugs, surgeries, and combination of both therapies for glaucoma intraocular ...
Muhammad Bagas Pratista   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Continuous growth of human footprint risks compromising the benefits of protected areas on the Qinghai-Tibet Plateau

open access: yesGlobal Ecology and Conservation, 2022
Protected areas (PAs) are the critical societal tool to preserve biodiversity and ecosystem services (ESs), but human disturbances frequently threaten them.
Ting Hua   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Intra-operative pressure sores [PDF]

open access: yes, 1995
As the extent of the pressure sore problem within hospitalized populations has been realized, their costs estimated and changes in the management of the NHS occurred, interest in pressure sores has increased and focused toward prevention.
Bridel, Jane Elizabeth
core  

Les forêts sacrées de l’aire Ouatchi au sud-est du Togo et les contraintes actuelles des modes de gestion locale des ressources forestières

open access: yesVertigO, 2005
This study was achieved in relict sacred forests, which are very important for their role as a safeguard of biodiversity in the human-populated region of southeast of Togo.
Kokou Kouami   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Investigating staff knowledge of safeguarding and pressure ulcers in care homes [PDF]

open access: yes, 2016
Objective: To investigate whether nursing/care home staff regard pressure ulceration as a safeguarding issue; and to explore reporting mechanisms for pressure ulcers in nursing/care homes.
Ousey, K.   +7 more
core   +1 more source

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