Results 101 to 110 of about 3,563,145 (300)
Exploring subjective career success using the Kaleidoscope Career Model
SA Journal of Industrial Psychology, 2019 Orientation: Currently, the workplace consists of four different generations of employees, of which the youngest, Generation Y (Gen Y), will become more prevalent in the next few years. Therefore, attracting and retaining employees of this generation are
Eileen Koekemoer, Anne Crafford
doaj +1 more source
Identify Critical Factors to Turn Workforce Satisfaction into Bottom-Line Results [PDF]
, 2010 KEY FINDINGS · While practitioners and researchers assume that higher employee satisfaction equals higher sales and profits, analysis shows that there is no direct link between the two.
Center for Advanced Human Resource Studies
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
CAHRS hrSpectrum (November - December 2006) [PDF]
, 2006 HRSpec06_12.pdf: 427 downloads, before Oct.
Center for Advanced Human Resource Studies
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Health Science ReportsBackground and Aims The prevalence of adverse childhood experiences (ACEs) is remarkably high in Bangladesh, and there is well‐documented evidence establishing a relationship between ACEs and mental disorders in children and adults.
Shamima Akter +3 more
doaj +1 more source
CAHRS hrSpectrum (January - April 2007) [PDF]
, 2007 HRSpec07_02.pdf: 192 downloads, before Oct.
Center for Advanced Human Resource Studies
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Beyond Tenure: Building Managerial Competencies through Developmental Assignments [PDF]
, 2009 Key Findings: • The developmental quality of job assignments is critical for building managerial competencies. What matters most isn’t how long junior managers have been in an assignment, but the nature of that assignment. • Not all junior
Center for Advanced Human Resource Studies, ILR School, Cornell University
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source