Results 51 to 60 of about 3,563,145 (300)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Two decades of qualitative research in Psychology, Industrial and Organisational Psychology and Human Resource Management within South Africa: A critical review

open access: yesSA Journal of Industrial Psychology, 2016
Orientation: Qualitative research is marked by phenomenal growth and development over the years. Research purpose: This article aims to offer insight into the emerging qualitative methodologies used in the fields of Psychology, Industrial and ...
Sumari O'Neil, Eileen Koekemoer
doaj   +1 more source

Should Personality Testing Be Part of the Hiring Process? [PDF]

open access: yes, 2010
KEY FINDINGS · Job candidates who fail a personality test the first time often change their responses dramatically on the second test—even though adult personality is known to be generally stable and unlikely to change in the short interval (in this ...
Center for Advanced Human Resource Studies
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Emotional Works and Turnover Intention of Sri Lankan Nurses

open access: yesKelaniya Journal of Management, 2017
In the quest for the concept of emotional work, it is apparent that comparing to the international context there are much less research done in Sri Lanka.
M.K. Dinithi Padmasiri, A.M.T. Lakmali
doaj   +1 more source

Procedural Justice in Selection from the Lens of Psychological Contract Theory

open access: yesOrganizacija, 2020
Background and purpose: In recruitment and selection, job applicants do not only base their justice judgment on the actual experience but also compare what happens and what they expect.
Huy Phuong Tran   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Starting Off on the Right Foot: Take Proactive Measures to Enhance Project Teams\u27 Performance [PDF]

open access: yes, 2012
Key Findings • The period between a project’s initiation and the project team’s first meeting is a crucial time that can significantly affect the team’s success • Team leaders can use this time effectively to lay the groundwork for their team’s ...
Center for Advanced Human Resource Studies
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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