Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Rethinking Human Resources for Health Planning in Labour Markets Disrupted by Conflict-Affected and Fragile Settings Comment on "Human Resources for Health in Conflict Affected Settings: A Scoping Review of Primary Peer Reviewed Publications 2016-2022". [PDF]
Aziz R.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Retraction Note: Pets at work: integrating pet-friendly initiatives into human resources for enhanced workplace harmony. [PDF]
Junça-Silva A, Galrito M.
europepmc +1 more source
Human resource accounting model for the valuation of human resources
منابع انسانی ماهر و متخصص برای یک سازمان همانند دارائیها و سرمایه گذاریهای آن سازمان دارای اهمیت اساسی است. مدیران سازمانها به منظور افزایش کارائی سازمان تحت سرپرستی خود همواره مبالغ هنگفتی را صرف آموزش و پرورش کارگران و کارمندان می نمایند اما معمولا مدیران اطلاعات جامعی در مورد ارزش اقتصادی منابع انسانی و میزان آموزش و تخصص آنها ندارند.
openaire +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Equity in the allocation of professional public health human resources and its improvement path in China. [PDF]
Liu Y +6 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Examining the supply and need of health workforce in Ethiopia: A foundation for strategic investment in human resources for health. [PDF]
Ali JM +9 more
europepmc +1 more source

