Results 101 to 110 of about 2,031,475 (315)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Selecting and training candidates to suit their role

open access: yesCommunity Eye Health Journal, 2018
Training the eye team can improve individual and community eye health – provided the right people are trained, and in the right way.
Dhivya Ramsamy, Daksha Patel
doaj  

Fiscal Year 1981

open access: yes, 1981
Annual report of the Texas Department of Human Resources describing goals, activities, and accomplishments during fiscal year ...
Texas. Department of Human Resources.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Human Resources Strategic Management [PDF]

open access: yesRevista de Management Comparat International, 2009
The most of the specialists value the role of the strategies and the tactics in modern societies development, including in the economic field, especially in increasing the companies effectiveness, but also for mezo, macro and worldwide economic levels.
Emil Surlaru
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Human Resources for eye health: ensuring a smooth pipeline

open access: yesCommunity Eye Health Journal, 2018
Health workforce planning improves when activities in the education system align with labour market dynamics.
Daksha Patel
doaj  

Analysis of the Teaching Staff in the Pre-University Education System [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
In order to realize the activities and achieve the expected results, the pre-university education institutions use several categories of resources, including the human resources that play an important role.
Todea Nicolae, Vitan Daniela
doaj  

Domestic scan results. [PDF]

open access: yes
Departments of Transportation are facing a critical shortage of qualified workers. In part due to this situation, the NMSHTD in consultation with the FHWA, the AASHTO Human Resources Committee, the NTTD, and the University of New Mexico carried out a ...
Hood, Jacqueline N.   +1 more
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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