Results 81 to 90 of about 1,718,068 (266)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Selecting and training candidates to suit their role

open access: yesCommunity Eye Health Journal, 2018
Training the eye team can improve individual and community eye health – provided the right people are trained, and in the right way.
Dhivya Ramsamy, Daksha Patel
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Reconfiguring agency under platform governance: Baby Boomer and Generation X singers negotiating identity, algorithms, and monetization

open access: yesFrontiers in Sociology
IntroductionDigital platforms have reconfigured the organization of music markets through algorithmic curation, metricized visibility, and increasingly formalized copyright regimes.
Ashanti Hastuti   +2 more
doaj   +1 more source

The Human Resources Strategic Management [PDF]

open access: yesRevista de Management Comparat International, 2009
The most of the specialists value the role of the strategies and the tactics in modern societies development, including in the economic field, especially in increasing the companies effectiveness, but also for mezo, macro and worldwide economic levels.
Emil Surlaru
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Human Resources for eye health: ensuring a smooth pipeline

open access: yesCommunity Eye Health Journal, 2018
Health workforce planning improves when activities in the education system align with labour market dynamics.
Daksha Patel
doaj  

Analysis of the Teaching Staff in the Pre-University Education System [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
In order to realize the activities and achieve the expected results, the pre-university education institutions use several categories of resources, including the human resources that play an important role.
Todea Nicolae, Vitan Daniela
doaj  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Ophthalmic nursing services in Botswana

open access: yesCommunity Eye Health Journal, 2014
Ophthalmic nurses make up 90% of all eye workers in Botswana’s public sector, and they are the only eye professionals being trained inside the country.
Chatawana Molao
doaj  

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