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Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Selecting and training candidates to suit their role
Training the eye team can improve individual and community eye health – provided the right people are trained, and in the right way.
Dhivya Ramsamy, Daksha Patel
doaj
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Analysis of the Teaching Staff in the Pre-University Education System [PDF]
In order to realize the activities and achieve the expected results, the pre-university education institutions use several categories of resources, including the human resources that play an important role.
Todea Nicolae, Vitan Daniela
doaj
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Human Resources for eye health: ensuring a smooth pipeline
Health workforce planning improves when activities in the education system align with labour market dynamics.
Daksha Patel
doaj
IntroductionDigital platforms have reconfigured the organization of music markets through algorithmic curation, metricized visibility, and increasingly formalized copyright regimes.
Ashanti Hastuti +2 more
doaj +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Ophthalmic nursing services in Botswana
Ophthalmic nurses make up 90% of all eye workers in Botswana’s public sector, and they are the only eye professionals being trained inside the country.
Chatawana Molao
doaj
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source

