Results 41 to 50 of about 5,905,785 (344)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

HUMAN RESOURCES AND HUMAN RESOURCES STRATEGY – STRATEGIC PARTNERS OF AN ORGANIZATION [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
This work is purely theoretical, based on information in the literature, but also on their correlations. The text does not have a generalized, but are personal opinions and conclusions.
MUNTEANU ANCA-IOANA
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

HUMAN RESOURCES AUDIT – PART OF HUMAN RESOURCES MANAGEMENT WITHIN AN ORGANIZATION [PDF]

open access: yesEconomica, 2017
In this article, we wanted to highlight one of the key components of human resources management – the audit. Although this term is fairly old and widely used in the economic field, with reference to human resources audit is a concept that emerged in ...
Ala COTELNIC, Ludmila NEGRUTA
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Human resources development in Nigerian commercial banks: An empirical investigation [PDF]

open access: yesManagement Science Letters, 2012
Human resources development is one of the management functions that are aimed at maximizing the return on the investments. It is a combination of training and education that ensure continual improvement and growth of all stakeholders.
Olalekan Anthony Sotunde, Akeem Salami
doaj  

The construct validity of the revised job diagnostic survey

open access: yesSouth African Journal of Business Management, 2007
The Job Characteristics Model, the accompanying Job Diagnostic Survey (JDS) and the proposed steps for improving motivation, satisfaction and performance have been functionally utilized in South Africa as a revised job redesign practice to address some ...
M. A. Buys, C. Olckers, P. Schaap
doaj   +1 more source

Strategic Human Resources Management: Human Resources or Human Capital

open access: yesAcademic Journal of Interdisciplinary Studies, 2013
Knowing that many or majority of companies do have human resources management department, there are some companies that have human capital management. Even these departments may not have to many differences they are slightly diverse. Strategic human resource management usually is inner company’s department which is erected or created with aim of ...
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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