Results 51 to 60 of about 4,808,406 (303)

The influence of global intellectualization on human development [PDF]

open access: yes, 2019
In the context of the global intellectualization, human capital is the determining factor in the innovation development and the international competitiveness of countries. In the XXI century.
S. Sardak, A. Samoilenko, Sardak, Sergii
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Targeted recombination of homologous chromosomes using CRISPR‐Cas9

open access: yesFEBS Open Bio, 2023
CRISPR mutagenesis is an efficient way to disrupt specific target genes in many model organisms. We previously devised a targeted CRISPR recombination method to generate intragenic recombinants of alleles in Drosophila.
Wonseok Son, Ki Wha Chung
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

RETRACTED: Conceptual Paper

open access: yesSAGE Open, 2012
“Conceptual Paper: Organizational Learning and Its Practices” by Mayuk Dasgupta, SAGE Open , February 1, 2012, DOI: 10.1177 ...
Mayuk Dasgupta
doaj   +1 more source

Profit Sharing in Multinational Corporations

open access: yesSouth African Journal of Business Management, 1975
Multinational corporations are proliferating through­out the world. They are coming not only from the United States, but from Europe and Asia as well. The purpose of this article is to build a case around which is based the concept that profit sharing ...
Charles W. Eisemann
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Human Resources, Poverty, and Regional Development [PDF]

open access: yes
Human development has moved to centre stage in development theory. Education makes an important contribution to economic growth, but achievement of mass education is important for a number of other reasons as well.
Gavin W. Jones
core  

A case study investigation of academic library support for open educational resources in Scottish universities [PDF]

open access: yes, 2019
The aim of the research was to investigate why and how Scottish university libraries support open educational resources and to assess their ability to provide support services for their development and use within higher education institutions.
Muir, Adrienne, Thompson, Seth D.
core   +3 more sources

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