Results 61 to 70 of about 4,808,406 (303)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

International and local students' satisfaction of healthcare services

open access: yesJournal of Business Management and Accounting, 2011
This research aims to measure the international and local students’ satisfaction toward university healthcare services provided by one public university.
Aayed Qasem, Rohaizat Baharun
doaj  

Corporate governance, technological innovation, and corporate performance: Evidence from China

open access: yesHeliyon
Corporate governance plays an important role in achieving high-quality economic development and sustainable corporate development. In recent years, as listed companies face increasing challenges in social responsibility issues such as environmental ...
Yinlong Ma   +3 more
doaj   +1 more source

The Development of IT- Based Human Resources in Universitas Diponegoro

open access: yesE3S Web of Conferences, 2018
Universitas Diponegoro (Undip) is a legal entity State University. Therefore, Undip is required to improve the quality of service. Human resources are the important aspect in improving services in Undip.
Dwimawanti Ida Hayu   +1 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

STRUCTURE AND VALIDATION OF A CONTEXTUAL QUALITY OF LIFE SCALE FOR PEOPLE WITH INTELLECTUAL DISABILITIES IN SOCIAL SERVICES: AN ORGANIZATION-ORIENTED MEASURE FROM AN EXTERNAL PERSPECTIVE

open access: yesPerspectivas em Gestão & Conhecimento, 2013
The aim of this study is to develop and validate a scale on the Quality of Life (QoL) of people with intellectual disabilities as assessed by family members (external perspective).
Carolina Moliner   +3 more
doaj  

Intercultural competence in the context of youth non-governmental organisations’ international activities

open access: yesMokslas: Lietuvos Ateitis, 2011
Increasingly growing necessity for international cooperation of Lithuanian youth non-governmental organization is analyzed in the article. The appropriateness of intercultural competence development for enhancing international activities of Youth non ...
Alvydė Palaimaitė, Asta Radzevičienė
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Econometric model for analyzing HRD Funds absorption at regional level – North-East region [PDF]

open access: yes
The European Social Fund interventions in Romania in the field of Human Resources Development, as established in the National Strategic Reference Framework 2007- 2013, will assure investment in human capital, modernisation of education and training ...
Paul RINDERU
core  

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