Results 231 to 240 of about 2,739,043 (309)

Supporting General Practitioners to Deprescribe Benzodiazepines and Z-Drugs in Primary Care: Findings From a Modified Delphi Study. [PDF]

Basic Clin Pharmacol Toxicol
Oldenhof E, Pisegna M, Horowitz M, Wilson H, Gelb K, Trumble S, Andronis C, Tracy M, Zwar NA, Mau A, Chapman A, Staiger PK.   +11 more
europepmc   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Fight, Flight, Fawn, Freeze: Rethinking Substance Use Through a Stress Response Lens. [PDF]

Curr Addict Rep
Algarin AB, Lee JY, Zhan X.
europepmc   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source

Evaluation of brucellosis eradication strategies in water buffalo in a key dairy production area of southern Italy. [PDF]

Front Microbiol
Mascolo C, Mazzeo A, Maiuro L, Signoriello S, Ferrara C, Esposito M, Rosati S, Sorrentino E.   +7 more
europepmc   +1 more source

Online bipartite matching methodology for anti-epidemic resources allocation: an adaptive time window based on reinforcement learning. [PDF]

Front Public Health
Wu Z, Pang S, He S.
europepmc   +1 more source

Self-organization of common good usage and an application to Internet services. [PDF]

PNAS Nexus
Pires DL, Mancuso V, Castagno P, Ajmone Marsan M.   +3 more
europepmc   +1 more source

Dual function antibody targeting αvβ3 and PD-L1 provide a promising strategy for solid tumor therapy. [PDF]

Front Immunol
Li G, Li W, Wang L, Bi Y, Wang Y, Zheng X, Hao R, Yin Y, Yu Y, Mu H, Li J, Ma X, Zhou S, Han J, Wang G, Huang R.   +15 more
europepmc   +1 more source