Results 51 to 60 of about 2,739,043 (309)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Inclusion of People with Disabilities in the Workplace: Best Practices for HR Professionals [PDF]
, 2016 [Excerpt] More than ever, companies are focused on developing a diverse workforce. However, disability is an often forgotten minority group. 1 in 5 people will acquire a disability in their lifetime, and individuals with disabilities are a major source ...
Collier, Danielle
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Strategic HR: Outsource Yourself? [PDF]
, 2010 [Excerpt] Human Resources has undergone a major transformation over the past three decades. Instead of solely pursuing a functional approach of delivering services, HR professionals now seek to develop and support the critical firm capabilities that ...
Fowler-Guzzardo, Evan M.
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Evolution of Human-like Social Grooming Strategies regarding Richness and Group Size
, 2018 Human beings tend to cooperate with close friends, therefore they have to construct strong social relationships to recieve cooperation from others.
Ichinose, Genki, Takano, Masanori
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Las Prácticas de Alto Rendimiento en Recursos Humanos: el Caso Español
Tec Empresarial, 2013 La presente investigación tiene como objetivoprioritario ahondar en el conocimiento sobre la tipologíae intensidad del uso en las empresas españolas de lasdenominadas Prácticas de Alto Rendimiento de recursoshumanos.
Roberto Luna Arocas +1 more
doaj
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Volunteering Reinvented: Human Capital Solutions for the Nonprofit Sector [PDF]
, 2007 To grow and adapt in today's continuously changing society, a nonprofit organization must recognize the value and contribution of both its paid staff and volunteers.
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