Results 131 to 140 of about 133,164 (249)

The Role of Mitochondrial Homeostasis in the Pathogenesis of Chronic Rhinosinusitis

Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
The vicious cycle between pathogenic factors‐induced inflammation, oxidative stress, and mitochondrial dysfunction in the context of chronic rhinosinusitis. Created in BioRender. Taghizadeh‐Hesary (2026) https://BioRender.com/k5f4t1f. ABSTRACT Background Chronic rhinosinusitis (CRS) is a common clinical condition characterized by persistent ...
Babak Ghalehbaghi, Morteza Fallahpour, Mohammad Nabavi, Maryam Jalessi, Hadi Ghanbari, Nasibeh Khayer, Farzad Taghizadeh‐Hesary   +6 more
wiley   +1 more source

Human Respiratory Syncytial Virus and Human Metapneumovirus

, 2009
The human respiratory syncytial virus (hRSV) and the human metapneumovírus (hMPV) are main etiological agents of acute respiratory infections (ARI). The ARI is an important cause of childhood morbidity and mortality worldwide.  hRSV and hMPV are members of the Paramyxoviridae.
da Silva, Luciana Helena Antoniassi, Spilki, Fernando Rosado, Riccetto, Adriana Gut Lopes, Baracat, Emilio Elias, Arns, Clarice Weis   +4 more
openaire   +1 more source

Plasma Interleukin‐10 Levels and IL10 Genetic Variants Are Associated With Clinical Outcomes in Patients With Severe COVID‐19 Treated With Corticosteroids

Journal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT We aimed to evaluate the association between IL10 variants and plasma IL‐10 levels and clinical outcomes in patients with severe COVID‐19 treated with corticosteroids. We studied 944 patients with severe COVID‐19 who were treated with corticosteroids.
Ingrid Fricke‐Galindo, Francisco M. Ortega‐Villafuerte, Gloria Pérez‐Rubio, Ivette Buendía‐Roldán, Julián Ramírez‐Bello, Azael A. Castillo Morales, Leslie Chávez‐Galán, Rafael de Jesús Hernández‐Zenteno, Espiridión Ramos‐Martínez, Salvador García‐Carmona, Daniela Josefina Cataneo‐Piña, Nora Edith Bautista‐Félix, Ramcés Falfán‐Valencia   +12 more
wiley   +1 more source

Therapeutic and Prophylactic Agents for Viral Diseases: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 11, November 2026.
This review summarizes current therapeutic and prophylactic strategies for global viral diseases, including vaccines, PrEP, direct‐acting antivirals, and emerging modalities such as CRISPR and siRNA. It highlights their clinical impact, ongoing challenges, and future priorities toward broader protection, improved delivery, and more effective antiviral ...
Sawar Khan, Ayesha Nisar, Xiaoxu Li, Hao Yu, Abdul Qadeer, Sardar Azhar Mehmood, Imane Lamraoui, Sijie Liu, Lipeng Zhu, Xu Deng, Bo Kong, Kejun Zhong, Zanxian Xia   +12 more
wiley   +1 more source

Inhaled Nanomedicines for Lung Diseases and Injuries: Pharmacological Advances and Clinical Translation

MedComm, Volume 7, Issue 11, November 2026.
Graphical overview of bioinspired regenerative platforms designed to remodel the diseased lung microenvironment. These systems integrate gene addition, siRNA‐mediated transcript silencing, CRISPR‐based modulation, and base editing approaches to promote alveolar repair, AT2‐to‐AT1 regeneration, resolution of inflammation, and restoration of vascular ...
Kajal Kamra, Sonal Gaur, Jaswinder Singh
wiley   +1 more source

Mitochondria in Viral Infections: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 11, November 2026.
Viral infections remodel mitochondrial function through direct viral regulation and infection‐induced changes in host cellular processes. These alterations affect OXPHOS, mitochondrial metabolism, calcium homeostasis, membrane potential, redox regulation, dynamics, and apoptosis, with distinct effects on viral replication and host antiviral responses ...
Ha Young Oh, Hye Jin Shin
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Respiratory Syncytial Virus Vaccination Is Associated With Increased Odds of Preterm Birth

Acta Paediatrica, Volume 115, Issue 11, Page 2473-2477, November 2026.
ABSTRACT Aim To analyse whether respiratory syncytial virus (RSV) vaccination during pregnancy increases the odds of preterm birth. Methods A rapid review and meta‐analysis was performed. The main outcome was the risk of preterm (gestational week less than 37) birth.
Ilari Kuitunen, Marjut Haapanen
wiley   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, Volume 115, Issue 11, Page 2380-2388, November 2026.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Human Respiratory Syncytial Virus [PDF]

, 2020
openaire   +1 more source