Results 141 to 150 of about 133,164 (249)
Determinants of respiratory syncytial virus and human metapneumovirus transmission
SUMMARY Respiratory syncytial virus and human metapneumovirus are major causes of respiratory illness globally, particularly affecting children and older adults. Despite their clinical significance, substantial gaps persist in understanding the determinants of their transmission.
David A. Foley +5 more
openaire +3 more sources
Health Science Reports, Volume 9, Issue 11, November 2026.
Oluwakemi D. Alonge +7 more
wiley +1 more source
Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley +1 more source
Advances in Cytosolic dsRNA Sensing of Viral Infections
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley +1 more source
ABSTRACTBackgroundIn Australia, non‐pharmaceutical interventions introduced early in 2020 to curtail the spread of COVID‐19 resulted in the temporary elimination of influenza. We used data from this influenza‐free period (2021) to validate influenza mortality burden predictions from time‐series models.MethodsTime‐series models were parameterised with ...
Jessie J. Goldsmith +4 more
wiley +1 more source
The Cytokine Response of Circulating Immune Cells to Rhinovirus (RV‐A16) is Reduced in Severe Asthma
ABSTRACT Severe asthma patients (SA) are more susceptible to respiratory infections with human rhinoviruses (HRV) than healthy subjects (H), causing exacerbations. In response to HRV, circulating immune cells are recruited to and activated at the local sites of infection.
Kaschin Jamal Jameel +10 more
wiley +1 more source
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less ribonucleoprotein condensates that assemble via liquid–liquid phase separation in the cytoplasm when translation initiation is impaired. SG formation commonly accompanies translational repression and may subsequently redistribute selected RNAs and signalling proteins, thereby linking cellular ...
Seoyeon Jo +2 more
wiley +1 more source
Not a Lost Art: A Practical Guide to Key Techniques and Recent Innovations in Protist Culturing
ABSTRACT Protists represent the majority of eukaryotic diversity and play essential roles in ecosystems worldwide. Obtaining protist species in culture permits in‐depth studies that provide insights into their cell biology, physiology, and biochemistry, and can transform them into valuable laboratory models representing lineages beyond plants, fungi ...
Daniel J. Richter +11 more
wiley +1 more source
Cytokine Profile Changes in Infants With Respiratory Syncytial Virus Bronchiolitis With Nirsevimab
Pediatric Pulmonology, Volume 61, Issue 11, November 2026.
José Antonio Cañas +9 more
wiley +1 more source
Outcomes After Respiratory Virus Detection Prior to Pediatric Solid Organ Transplantation
ABSTRACT Background Respiratory viral infections are associated with increased pulmonary morbidity in immunocompromised populations. It is not known whether pediatric solid organ transplant (SOT) recipients who test positive for respiratory viruses prior to transplant have increased risk of adverse pulmonary outcomes.
Mallory Go +4 more
wiley +1 more source

