Results 41 to 50 of about 583,958 (266)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Should politicians be prosecute for statements made in the exercise of their mandate?
Crítica Penal y Poder, 2019 http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-en.asp?fileid=25279&lang=en http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-FR.asp?fileid=25279&lang ...
Boris Cilevičs, Committee on Legal Affairs and Human Rights
doaj
TortureIntroduction. This article examines the violations of International Humanitarian Law (IHL) concerning Israeli attacks on medical personnel and facilities in Lebanon between September 23rd and October 23rd, 2024. Methods. Based on data from the Lebanese
Sarah Nasrallah +3 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Review of Regional Development Planning Based on the Human Rights Principles
Jurnal Bina Praja, 2017 The current development paradigm is still dominated by the neoclassical economic perspective which sees economic development as a mechanical and simplistic process, without the need to look at aspects of respect, protection, and fulfillment of human ...
Pihri Buhaerah +2 more
doaj +1 more source
The Holders of Human Rights [PDF]
, 2020 Abstract International human rights law and practice reveal an ambivalent approach to the personal scope of human rights: human rights are often less equal or general than they claim and are claimed to be. The inequalities of human rights are of two kinds: some vulnerable individuals are also protected by special rights, thus drawing an ...
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
“What is there left after losing oneself?”: 100 testimonies of genocidal torture from Gaza
TortureIntroduction: Since 7 October 2023, the number of Palestinians detained by Israeli authorities has increased dramatically. Methods: Semi-structured in-depth interviews were conducted between December 2023 and November 2024 with 100 Palestinians who ...
Maha Aon +7 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Frontiers in AgingBackgroundUnwanted loneliness among older adults has become a growing public health concern, particularly in rural contexts characterized by population aging, depopulation, and limited access to services.
A. Yurrebaso +3 more
doaj +1 more source