Results 41 to 50 of about 10,020,685 (308)

Israeli attacks against medical personnel and facilities in Lebanon: A violation of International Humanitarian Law

Torture
Introduction. This article examines the violations of International Humanitarian Law (IHL) concerning Israeli attacks on medical personnel and facilities in Lebanon between September 23rd and October 23rd, 2024. Methods.
CLDH CLDH, Fadel Fakih, Anthony Hanna, Hasna Abdel Reda   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Should politicians be prosecute for statements made in the exercise of their mandate?

Crítica Penal y Poder, 2019
http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-en.asp?fileid=25279&lang=en http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-FR.asp?fileid=25279&lang ...
Boris Cilevičs, Committee on Legal Affairs and Human Rights
doaj  

SANITARY-AND-EPIDEMIOLOGIC WELL-BEING OF CHILDREN IN THE RUSSIAN FEDERATION

Педиатрическая фармакология, 2013
The article provides a morbidity analysis and covers the epidemiologic process development tendencies in the Russian Federation for a range of infectious diseases, including those controlled by specific preventive measures, and the measures taken to ...
G. G. Onishchenko, E. B. Ezhlova, A.A. A.A. Melnikova, L. A. Dementyeva, Y. V. Demina, G. V. Yanovskaya, N. A. Fedotova, G. E. Ivanov   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

“What is there left after losing oneself?”: 100 testimonies of genocidal torture from Gaza

Torture
Introduction: Since 7 October 2023, the number of Palestinians detained by Israeli authorities has increased dramatically. Methods: Semi-structured in-depth interviews were conducted between December 2023 and November 2024 with 100 Palestinians who ...
Maha Aon, Natacha Bracq, Lisa Michaelsen, Tina Søndergård Madsen, Basel Alsourani, Yasser Abdel Ghafour, Hamdi Shaqqura, Raji Alsourani   +7 more
doaj   +1 more source

Review of Regional Development Planning Based on the Human Rights Principles

Jurnal Bina Praja, 2017
The current development paradigm is still dominated by the neoclassical economic perspective which sees economic development as a mechanical and simplistic process, without the need to look at aspects of respect, protection, and fulfillment of human ...
Pihri Buhaerah, Nurrahman Aji Utomo, Elfansuri Elfansuri   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Unwanted loneliness among older adults in rural areas: associated factors and guidelines for community intervention

Frontiers in Aging
BackgroundUnwanted loneliness among older adults has become a growing public health concern, particularly in rural contexts characterized by population aging, depopulation, and limited access to services.
A. Yurrebaso, E. Picado-Valverde, E. García-Valverde, R. Guzmán-Ordaz   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source