Results 51 to 60 of about 10,020,685 (308)
, 2017 Our 2016-2017 Annual Review is dedicated to our friend and colleague Barbara Harlow (1948-2017). It outlines our continued efforts to examine the relationship between economic inequality and human rights, spotlights fieldwork and internships undertaken ...
Rapoport Center for Human Rights and Justice
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
War and peace: the ANZAC spirit and human rights [PDF]
, 2015 A series of papers given by the various speakers at the Australian Human Rights Commission’s War and Peace: The Anzac spirit and human rights 2014 seminar. Summary Every year around Anzac Day, Australians and New Zealanders remember those who fought in
Australian Human Rights Commission
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Depression and Anxiety among Iraqi Women: A Systematic Review
Erbil Journal of Nursing and Midwifery, 2018 Background and objective: Maternal mental health is considered an important subject among leading public health experts. Women are two to three times more likely to be diagnosed with mental illness compared to men.
Kathryn Mishkin +3 more
doaj +1 more source
Humans Rights Against Human Rights
Counterfutures, 2021 Review of Jessica Whyte, The Morals of the Market: Human Rights and the Rise of Neoliberalism. A new history of the parallel rise of neoliberalism and human rights.
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source