Results 71 to 80 of about 9,596,602 (303)
Islandness in human rights, human rights in islandness: Missing voices
Island Studies literature has rarely engaged with human rights law to scrutinise how the development of human rights standards and/or their (in)efficient implementation on islands contour the lives of islanders and islandness itself. Along similar lines, human rights research and practice do not systematically take into account islandness and Island ...
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Background Since the Hamas attacks in Israel on 7 October 2023, the Israeli military has launched an assault in the Gaza Strip, which included over 12,000 targets struck and over 25,000 tons of incendiary munitions used by 2 November 2023. The objectives
Yara Asi +12 more
doaj +1 more source
For years, social media platforms have been perceived as a democratic gain, facilitating freedom of expression, easy access to a variety of information, and new means of public participation.
Jørgensen Rikke Frank, Zuleta Lumi
doaj +1 more source
HUMAN RIGHTS AND THE PALESTINIANS
Tt is gratifying that concern for human rights is global.There is also a general consensus that respect for human rightsought to be indivisible. The community described as "Palestinian" and that vvhich identifies itself as "Israel" may be betterunderstood and their role in history better evaluated if one assesses the human rights ...
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Other title: Employment Law's Clark Kent; Other title: ow You Can be a Superhero, Too!
"7/7/2017."Kansas Human Rights Commission -- Harassment: Demonstrating "Reasonable Care" -- The Complaint Process -- The Investigation -- Disability: Engaging in the Interactive ...
Kansas Human Rights Commission.
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Pathways to protection: a human rights-based response to the flight of asylum seekers by sea [PDF]
The Commission has endeavoured to identify options for responding to flight by sea which are consistent with Australia’s international human rights obligations.
Australian Human Rights Commission
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