Results 101 to 110 of about 1,602,123 (303)

Timor link, no. 34, November 1995 [PDF]

open access: yes, 1995
Contents: Eyewitness account -- A 'second invasion' -- Bishop Belo calls for dialogue -- Appeal to Beijing conference -- Human rights update -- UN decolonisation committee -- Boutros- Ghali reports -- UN subcommission -- Socialists elected in Portugal --

core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Access to an Effective Remedy in European Asylum Procedures [PDF]

open access: yes, 2008
In this contribution the author tries to identify the meaning and content of the Community principles of effectiveness and effective judicial protection with regard to the right of access to an effective remedy in the context of the Common European ...
Reneman, A.M.
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Walking to the Altar? Equal Marriage in International Human Rights Law

open access: yesIuris Dictio, 2018
This text states that, in these last two decades, International Human Rights Law has been a brake for the recognition of equal marriage at the supranational level.
Carlos J. Zelada
doaj   +1 more source

Committees: Human Rights Bodies [PDF]

open access: yes, 2019
1 ‘Human rights bodies’ are international and regional non-judicial bodies which address human rights issues, normally under a particular treaty. For the purposes of this entry, ‘human rights bodies’ only includes bodies which receive and deal with complaints about human rights abuses, or those which will have that capacity once the treaty that creates
openaire   +1 more source

The Shackling of Incarcerated Pregnant Women: A Human Rights Violation Committed Regularly in the United States [PDF]

open access: yes, 2013
The international human rights community has repeatedly expressed concern about the shackling of pregnant women deprived of their liberty in the United States.
Aaron Lee   +3 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Protecting and Promoting the Human Right to Respect for Family Life: Treaty-Based Reform and Domestic Advocacy [PDF]

open access: yes, 2010
This article examines the right to respect for family life in international law, focusing on its underlying principles and explicit protections. The article identifies these legal norms so that drafters of international treaties, specifically the ...
Mrazik, Ryan, Schoenholtz, Andrew I.
core   +1 more source

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