Results 101 to 110 of about 10,769,743 (299)
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Immediate Release, August 17, 2012
, 2012 "August 17, 2012.""The Kansas Human Rights Commission (KHRC) is pleased to announce that Robert G. Lay, formerly of Topeka, Kansas, and Rehelio "Ray" A.
Kansas Human Rights Commission.
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The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
The United Nations Human Rights Committee and the International Law of Indigenous Peoples’ Rights
Revista Electrónica IberoamericanaThe United Nations Declaration on the Rights of Indigenous Peoples, adopted in 2007, is the most comprehensive international instrument on the rights of Indigenous Peoples, but it did not create those rights, as evident in the work of the United Nations
S. James Anaya
doaj +1 more source
Submission to the Legal Affairs and Community Safety Committee on the Human Rights Bill 2018 [PDF]
, 2018 On 31 October 2018, the Human Rights Bill 2018 was introduced into the Queensland Parliament. The Bill is currently being considered by the Legal Affairs and Community Safety Committee which has issued a call for submissions. This submission, written by
Jones, Nicky, Patrick, Jeremy
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MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Panel debate on ensuring human rights in the global economy : the role of the WTO
, 1999 Panel debate co-organized by International NGO Committee on Human Rights in Trade and Investment (INCHRITI). Panelists include: Sakiko Fukada-Parr (Human Development Report Office, UNDP), Alec Irwin (Minister of Trade and Industry, South Africa), Peter ...
People's Decade for Human Rights Education (PDHRE)
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FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
, 2016 Our 2015-2016 Annual Review highlights the first year of our five-year project on inequality and human rights, fieldwork and internships undertaken by students across campus, and the first Sissy Farenthold Endowed Lecture ...
Rapoport Center for Human Rights and Justice
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