Results 61 to 70 of about 10,145,519 (298)

Freedom of opinion and expression in the ICCPR Human Rights Committee’s General Observation No. 34

Anuario de Derechos Humanos, 2012
In 2011 the Human Rights Committee brought out General Comment No. 34 on the right to freedom of opinion and expression. This article explores the content of this document by first evaluating the way in which the Committee interprets the positive sphere ...
Simón Conforti
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Human rights scrutiny report: report 1 of 2017

, 2017
Under the Human Rights (Parliamentary Scrutiny) Act 2011, the committee is required to examine bills, Acts and legislative instruments for compatibility with human rights, and report its findings to both Houses of the Parliament.
Parliamentary Joint Committee on Human Rights
core  

The UN Human Rights Committee in Promoting Accountability for Gross Human Rights Violations in Indonesia

Human Rights in the Global South
Despite officially acknowledging past atrocities in 2023, Indonesia has yet to deliver justice or reparations for victims, prompting continued scrutiny from the United Nations Human Rights Committee (UN HRC). This article examines the extent to which the
Rozy Brilian Sodik
doaj   +1 more source

Cultural Identity in the Case-Law of the Human Rights Committee

Przegląd Prawniczy Uniwersytetu im. Adama Mickiewicza, 2017
The aim of the article is to present the jurisprudence of the Human Rights Committee on Article 27 of the International Covenant on Civil and Political Rights concerning the rights of persons belonging to ethnic, religious and linguistic minorities ...
Sylwia Stryjkowska
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Do not forget the Nubians: Kenya’s compliance with the decisions of African regional treaty bodies on the plight and rights of Nubians

De Jure, 2021
In 2006 and 2009, the African Commission on Human and People’s Rights (African Commission) and the African Committee of Experts on the Rights and Welfare of the Child (African Children’s Committee) respectively, received communications on behalf of the ...
Elvis Fokala
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

For The Many, Not the Few: Case Analysis of Bukit Duri Forced Eviction in Jakarta

Rechtsidee: Law Journal, 2018
The International Covenant on Civil and Political Rights and the International Covenant on Economic, Social and Cultural Rights allow states to conduct forced eviction as long as it is carried out within the given boundaries.
Arie Afriansyah
doaj   +1 more source