Results 71 to 80 of about 10,145,519 (298)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The International Covenants on Human Rights – 60 Years!
Московский журнал международного праваINTRODUCTION. The sixtieth anniversary of the adoption of the International Covenant on Economic, Social and Cultural Rights and the International Covenant on Civil and Political Rights brings renewed relevance to the question of their place within the ...
A. Kh. Abashidze
doaj +1 more source
Challenges and improvements in the rights of persons with disabilities: A global perspective
Anuario de Derechos Humanos, 2015 The United Nations Convention on the Rights of the Persons with Disabilities is the first human rights treaty of the 21st century, which established the human rights model for this part of the population. The Convention is structured around two main
María Soledad Cisternas Reyes
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
THE PROTECTION OF PERSONAL DATA - AN ESSENTIAL COMPONENT OF THE FUNDAMENTAL HUMAN RIGHTS [PDF]
Challenges of the Knowledge Society, 2019 In terms of human rights in general, and their promotion and protection, especially, developments have been and will continue to remain diverse and complex. This aspect addresses equally the concerns about the identification of human rights, as well as
Augustin FUEREA
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Other title: Employment Law's Clark Kent; Other title: ow You Can be a Superhero, Too!
, 2017 "7/7/2017."Kansas Human Rights Commission -- Harassment: Demonstrating "Reasonable Care" -- The Complaint Process -- The Investigation -- Disability: Engaging in the Interactive ...
Kansas Human Rights Commission.
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