Results 61 to 70 of about 107,539 (307)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
دراسة مقارنة بين لجنة حقوق الإنسان ومجلس الأمم المتحدة لحقوق الإنسان التشكيل والاختصاصات
مجلة الآداب و العلوم الإجتماعية, 2014 The UN was created in 1945 to care for humùan right after the numerous transgressions and crime against humanity. The UN Commission on Human Rightswas set up to preserve international peace. It proved inefficient because it was politcisedand dominated
نرجـس صفو
doaj
Zeszyty Prawnicze, 2016 The European Convention on the Adoption of Children as an Instrument of the Common Principles of the Member States of the Council of Europe on the Adoption of Children Summary Acting on the grounds of its statutory aims, the Council of Europe has ...
Elżbieta Hanna Morawska
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Modern Discourse of Human Rights: Main Issues and Contradictions
Дискурс Пи, 2019 The paper concerns discourses connected with human rights, human rights protection and education in human rights. Authors analyze a number of features that define the development of modern human rights discourses within activity of the UN and the Council
Glushkova S.I., Martynov K.E
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
STATE SOVEREIGNTY AND PROTECTION OF HUMAN RIGHTS
ACROSSThis article explores the concept of “state sovereignty” and its transformation into “divided sovereignty” upon a state’s ratification of the European Convention for the Protection of Human Rights and Fundamental Freedoms (hereinafter the Convention).
Stepan POPOVSCHII
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The United Nations Human Rights Council: A critique and early assessment
, 2011 PhDThe United Nations Human Rights Council was created in 2006 to replace the UN Commission on Human Rights. The Commission‘s failure had been attributed to its increasing politicisation and decreasing ability to discharge its mandate.
Freedman, Rosa
core
Scottish Council on Global Affairs Podcast: The Scottish Human Rights Bill
, 2023 On 15 June 2023, the Scottish Government published the long-awaited consultation on its plans to incorporate various UN human rights treaties into Scots law, subject to the limits of the devolved competence of the Scottish Parliament.
Scott, David M.
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source