Results 61 to 70 of about 89,677 (261)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Poverty - the violation of human rights

open access: yesRUDN Journal of Law, 2011
The eradication of poverty is one of the most vital issues facing the international community. Numerous international documents, including the Millennium Development Declaration and Goals, recognize the relationship between poverty and human rights.
A Kh Abashidze, A E Koneva
doaj  

IN MEMORIAM.

open access: yesRevista da Faculdade de Direito da Universidade Federal de Minas Gerais
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Andrew Drzemczewski, Dean Spielmann
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Dormant Rights and Initiatives on the Agenda of the UN Human Rights Council

open access: yesCzech Journal of International Relations, 2012
The issue of international human rights norms which have not yet been fully established within the existing international human rights standard belongs at present to the essential components of the UN Human Rights Council agenda. Based on a synthesis of
Štěpánka Zemanová   +1 more
doaj  

Challenges and Opportunities for a Local Government Implementing a Human Rights Policy in Australia

open access: yesUrban Planning
This article considers how a human rights culture in urban policymaking fits within wider theories of human rights cities. Specifically, it considers practical ways to bring together what local government officers consider the most important initiatives ...
Karien Dekker   +3 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Menstruation, Myopia, and Marginalization: Advancing Menstrual Policies to “Keep Girls in School” at the Risk of Exacerbating Inequalities [PDF]

open access: yesHealth and Human Rights, 2020
As countries across the world adopt policies addressing menstruation, it is imperative to identify who benefits from such policies and to understand the dynamics of inclusion and exclusion.
Nay Alhelou   +4 more
doaj  

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