Results 121 to 130 of about 6,884,140 (312)

AN OVERVIEW OF HUMAN RESOURCES IN SCIENCE AND TECHNOLOGY (HRST) FROM RESEARCH DEVELOPMENT AND INNOVATION (RDI) SECTOR DURING 1993-2009 IN ROMANIA [PDF]

open access: yes
The present paper present a study done on the Human Resources in Science and Technology (HRST) in Research Development and Innovation (RDI) sector in Romania during 1993-2009 .This paper started from the elements defined in Canberra Manual based on the ...
NICOLOV MIRELA
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The position of the Quran in the methodologyof the production of transcendental humanities with an emphasis on Imam Khomeini's thought [PDF]

open access: yes‫سیاست متعالیه‏, 2019
The main purpose of the present research is to use the Qur'an in the production of transcendental human sciences from the perspective of Imam Khomeini. This study is innovative in terms of explaining the relationship between the types of encountering the
REZA LAKZAEI
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

درنگی بر مفهوم علوم انسانی آلمانی (Geiteswissenschaft) [PDF]

open access: yesروش شناسی علوم انسانی, 2017
پرسش از چیستی علوم انسانی در ایران معاصر پرسشی زنده و پویاست. اینکه علوم انسانی به چه کار می‌آید؟ یا اینکه آیا علوم انسانی اصلاً باید به کاری بیاید؟ اینکه علوم انسانی با دین چه نسبتی دارد؟ و پرسش‌های بسیار دیگری اکنون میان صاحب‌نظران این حوزه در ایران ...
علیرضا منجمی
doaj  

NASA Ames Institutional Scientific Collection (ISC) [PDF]

open access: yes
NASA's current human space flight research is directed towards enabling human space exploration beyond Low Earth Orbit (LEO). The Space Flight Payload Projects; Rodent Research, Cell Science, and Microbial Labs, flown on the International Space Station ...
French, Alison J.   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Qualitative software engineering research -- reflections and guidelines

open access: yes, 2020
Researchers are increasingly recognizing the importance of human aspects in software development and since qualitative methods are used to, in-depth, explore human behavior, we believe that studies using such techniques will become more common ...
Feldt, Robert   +5 more
core  

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