Results 121 to 130 of about 2,753,266 (267)

Full Issue, Volume 5, Number 3

Journal of Human Sciences and Extension, 2017
Journal of Human Sciences and Extension
doaj  

PAMD-Ch17, a Polymeric Analog of Plerixafor, Induces Mitochondrial Dysfunction in T-ALL Cells Independent of CXCR4. [PDF]

Mol Cancer Ther
Lam C, Dhir A, Mitro A, Jogdeo CM, Panda S, Kapoor E, Tang S, Rivero VJ, McIntyre EM, Coulter DW, Xiao P, Black AR, Hewitt K, Romanova S, Swenson SA, Oupicky D, Hyde RK.   +16 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Full Issue, Volume 5, Number 1

Journal of Human Sciences and Extension, 2017
Journal of Human Sciences and Extension
doaj  

Fresh aboveground net primary productivity of Tibetan grasslands: Responses of different plant functional groups to climate change and human activities and implications for ecosystem management. [PDF]

PLoS One
Zhang G, Sun W, Li S, Zhong Z, Tian Y, Zhao C, Han F, Huang S, Yujie D, Fu G.   +9 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Full Issue, Volume 3, Number 3

Journal of Human Sciences and Extension, 2015
Journal of Human Sciences and Extension
doaj  

Etiology of severe acute respiratory infections among adults in northern Thailand using multiplex PCR: A post-COVID-19 surveillance study (2023-2024). [PDF]

PLoS One
Kham-Kjing N, Kawila R, Tariyo P, Puapun K, Wongchotbrorirak S, Ngo-Giang-Huong N, Hongjaisee S, Khamduang W.   +7 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Full Issue, Volume 3, Number 1

Journal of Human Sciences and Extension, 2015
Journal of Human Sciences and Extension
doaj