Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices [PDF]
Journal of Osseointegration Volume 7, Issue 1, 1 March 2015, Pages 2-7 Open Access Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices (Article) Pozzuoli, A.a, Gardin, C.b, Aldegheri, R.a, Bressan, E.c,
Aldegheri, R. +9 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Eden Inverted: On the Wild Self and the Contraction of Consciousness [PDF]
The conditions of hunting and gathering through which one line of primates evolved into humans form the basis of what I term the wild self, a self marked by developmental needs of prolonged human neoteny and by deep attunement to the profusion of ...
Halton, Eugene
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Reactivity in the human sciences
AbstractThe reactions that science triggers on the people it studies, describes, or theorises about, can affect the science itself and its claims to knowledge. This phenomenon, which we call reactivity, has been discussed in many different areas of the social sciences and the philosophy of science, falling under different rubrics such as the Hawthorne ...
Marchionni C., Zahle J., Godman M.
openaire +6 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Earth benefits from NASA research and technology. Life sciences applications [PDF]
This document provides a representative sampling of examples of Earth benefits in life-sciences-related applications, primarily in the area of medicine and health care, but also in agricultural productivity, environmental monitoring and safety, and the ...
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READING HAN FEI AS SOCIAL SCIENTIST : A CASE-STUDY IN HISTORICAL CORRESPONDENCE [PDF]
Han Fei was one of the main proponents of Legalism in Qin-era China. Although his works are mostly read from a historic perspective, the aim of this paper is to advance an interpretation of Han Fei as a social scientist.
Schneider, Henrique
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Comparison of health behaviors among students of Iranian medical and human sciences universities. [PDF]
Shohani M, Rasouli M.
europepmc +1 more source
A Review of Chinese Academy of Sciences (CASIA) Gait Database As a Human Gait Recognition Dataset [PDF]
Human Gait as the recognition object is the famous biometrics system recently. Many researchers had focused this subject to consider for a new recognition system.
Andrie , Rosa +2 more
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