Results 51 to 60 of about 294,711 (260)

Building morphologies of the USA structures database; a gauntlet feature set

Scientific Data
In recent years there has been a proliferation of methods and data to extract building footprints from satellite imagery. However there has been very little effort to provide additional insight about these buildings beyond their spatial location and ...
Taylor Hauser, Clinton Stipek, Nagendra Singh, Jessica Moehl   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Mindset shifts and sustainability transformation journeys across Urban Labs in Latin America

Urban Transformations
Cities are at the forefront of the climate crisis, requiring innovative approaches to foster sustainability transformations. Urban Labs offer a promising avenue for engaging diverse stakeholders and driving transformative change, yet the role of mindset ...
Flávia Guerra, Sneha Roy, Lionel Muñoz Rosas, Simone Sandholz   +3 more
doaj   +1 more source

Synergies and trade-offs in the management objectives forest health and flood risk reduction

Frontiers in Forests and Global Change, 2023
While healthy forest ecosystems deliver various services that can reduce flood risk, they can also contribute to flooding by providing wood that potentially contributes to the clogging of waterways and associated backwater effects.
Fabian Rackelmann, Fabian Rackelmann, Zita Sebesvari, Rainer Bell   +3 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Adversarial Learning Based Discriminative Domain Adaptation for Geospatial Image Analysis

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2022
The ability of supervised image analysis methods to provide state-of-the-art performance is limited by availability of high-quality labeled data in large quantities.
Nikhil Makkar, Lexie Yang, Saurabh Prasad   +2 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Moving towards a comprehensive evaluation of ecosystem-based disaster risk reduction: The example of agroforestry for flood risk reduction

Nature-Based Solutions
Nature-based solutions (NbS) have received increased interest as cost-effective contributors to addressing societal challenges, with ecosystem-based disaster risk reduction (Eco-DRR) being the specific approach for reducing disaster risk under the NbS ...
S. Janzen, J. Balzer, F. Merk, C. Eberle, A. Chabi, Y. Walz   +5 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source