Results 51 to 60 of about 2,533,685 (299)
Adversarial Learning Based Discriminative Domain Adaptation for Geospatial Image Analysis
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2022 The ability of supervised image analysis methods to provide state-of-the-art performance is limited by availability of high-quality labeled data in large quantities.
Nikhil Makkar +2 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Mindset shifts and sustainability transformation journeys across Urban Labs in Latin America
Urban TransformationsCities are at the forefront of the climate crisis, requiring innovative approaches to foster sustainability transformations. Urban Labs offer a promising avenue for engaging diverse stakeholders and driving transformative change, yet the role of mindset ...
Flávia Guerra +3 more
doaj +1 more source
Human Security, Individualism and Collectivism
Cadmus, 2023 The quest for human security has pitted the individual against the collective throughout history. Individualism and collectivism are two competing philosophical and social movements that have divided the world for centuries and trace their origin back to
Ashok Natarajan
doaj
Human Factors in Information Security [PDF]
, 2017 It is a well-know fact that there is no unbreakable system in the world. Nowadays, creating secure information system is a big challenge. Besides, it is a desired goal for all IT security managers and engineers in the world.
Kostrytska, S.I. +2 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Nature-Based SolutionsNature-based solutions (NbS) have received increased interest as cost-effective contributors to addressing societal challenges, with ecosystem-based disaster risk reduction (Eco-DRR) being the specific approach for reducing disaster risk under the NbS ...
S. Janzen +5 more
doaj +1 more source
Pathologies of Security Governance: Efforts Against Human Trafficking in Europe [PDF]
, 2007 The trafficking of women and girls for the purpose of sexual exploitation has reportedly been booming in Europe since the 1990s. Governments, international organizations, and private actors have addressed the causes and consequences of sex trafficking in
Friesendorf, Cornelius
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source