Results 21 to 30 of about 426,418 (303)
Punishing Pharmaceutical Companies for Unlawful Promotion of Approved Drugs: Why the False Claims Act is the Wrong Rx [PDF]
, 2008 This article criticizes the shift in focus from correction and compliance to punishment of pharmaceutical companies allegedly violating the Food, Drug, & Cosmetic Act (FD&C Act) prohibitions on unlawful drug promotion.
Girard, Vicki W.
core +2 more sources
Atmosphere, 2022 Rapid urban expansion leads to the continuous deterioration of the urban thermal environment, which endangers the sustainable development of the city; meanwhile, countries all over the world are becoming increasingly interested in the mitigating effects ...
Jiajie Hou +3 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Systems approaches to human settlements [PDF]
Papers of the Regional Science Association, 1977 Regional and urban policies always have consequences for the whole of the national territory, whether or not they were intended to do so. Thus policy makers should have a reasonably good grasp of the structure of human settlement systems and of the nature of the processes that underlie evolving settlement patterns.
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Improved governance and sustainable urban development Strategic planning holds the key
European Journal of Spatial Development, 2006 The recent focus on improved governance in cities has raised some concerns about the role of urban planning. Questions have been raised on whether good governance is a substitute for planning, and if it is adequate in itself to achieve sustainable ...
Shipra Narang, Lars Reuterswärd
doaj +3 more sources
Scientific ReportsUniversity open spaces are predominantly utilized by students, with outdoor thermal comfort on campus significantly enhancing their physical and mental well-being. This study investigates the thermal perceptions (sensation, comfort, and acceptability) of
Wenqiang Jing +6 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Mapping Human Settlements from Space [PDF]
, 2015 This booklet describes the Global Human Settlement Layer for mapping human presence using satellite imagesJRC.A.6 ...
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source