Results 161 to 170 of about 9,029,134 (304)

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

open access: yesAdvanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu   +18 more
wiley   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

open access: yesAdvanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo   +11 more
wiley   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

open access: yesAdvanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang   +8 more
wiley   +1 more source

Mathematical modelling of the half-sarcomere from a human skeletal muscle [PDF]

open access: yes
The character of the functional output of a motor unit within skeletal muscle has been linked experimentally to the proteins found in the sarcomere, the smallest contractile unit of muscle fibre.
Guest, Kay P.
core  

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise-Induced Redox Responses in Human Skeletal Muscle. [PDF]

open access: yesAging Cell
Ruple BA   +11 more
europepmc   +1 more source

High‐Performance Piezoresistive Sensors via Pd/Sn‐Free Graphene‐Catalyzed Metallization of Thermally Repairable Microfiber Scaffolds

open access: yesAdvanced Science, EarlyView.
The multilayer fiber‐based PGC sensor, fabricated via graphene‐mediated electroless copper deposition, demonstrates high sensitivity, mechanical durability, and fast response speed. Additionally, it features low‐temperature thermal assisted recovery and thermal resistance, providing a promising platform for wearable electronic devices and IoT ...
ByungJun Kim   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy