Results 51 to 60 of about 9,029,134 (304)
Aging affects the transcriptional regulation of human skeletal muscle disuse atrophy. [PDF]
PLoS ONE, 2012 Important insights concerning the molecular basis of skeletal muscle disuse-atrophy and aging related muscle loss have been obtained in cell culture and animal models, but these regulatory signaling pathways have not previously been studied in aging ...
Charlotte Suetta +13 more
doaj +1 more source
Distribution of caveolin in the muscle spindles of human skeletal muscle [PDF]
Journal of Anatomy, 2014 AbstractThe aim of the present study was to demonstrate the location of the different members of the caveolin (cav) family in human muscle spindles. Twenty spindles of three human muscles (vastus medialis, ischiocavernosus, bulbospongiosus) from 12 cadavers were immunohistochemically stained for cav‐1, cav‐2, and cav‐3, and the equatorial and polar ...
Kevin, Peikert +2 more
openaire +2 more sources
CONSTRUCTIVE TISSUE REMODELING BY EXTRACELLULAR MATRIX BIOSCAFFOLDS WITHIN THE AGING SKELETAL MUSCLE MICROENVIRONMENT [PDF]
, 2013 Adult mammalian skeletal muscle tissue retains inherent regenerative capability in response to injury. This regenerative response is contingent upon an activated progenitor cell population and a temporal transition from pro-inflammatory M1 to ...
Sicari, Brian
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Imaging displacement and strain in the medial gastrocnemius muscle during ankle-joint motion using 2D-ciné DENSE MRI [PDF]
, 2011 Skeletal muscle structure has been defined on both macro and microscopic levels by gross dissection, light- and electron-microscopy. The basic physiological building blocks involve the electromechanical coupling between interlinking actin and myosin ...
Lawson, Andrew James
core +1 more source
The role of adipokines in skeletal muscle inflammation and insulin sensitivity
Journal of Inflammation, 2018 Background There is currently an unmet clinical need to develop better pharmacological treatments to improve glucose handling in Type II Diabetes patients with obesity.
Thomas Nicholson +3 more
doaj +1 more source
PGC-1α modulates skeletal muscle regeneration by affecting immune response and satellite cell behavior [PDF]
, 2014 The benefits of exercise on wellbeing have been known to mankind for thousands of years, yet the underlying mechanisms of exercise have been explained only relatively recently.
Dinulović, Ivana
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Molecular Metabolism, 2017 Objective: Strategies improving skeletal muscle mitochondrial capacity are commonly paralleled by improvements in (metabolic) health. We and others previously identified microRNAs regulating mitochondrial oxidative capacity, but data in skeletal muscle ...
Dennis Dahlmans +8 more
doaj +1 more source
Sphingosine-1-Phosphate Signaling Regulates Myogenic Responsiveness in Human Resistance Arteries. [PDF]
PLoS ONE, 2015 We recently identified sphingosine-1-phosphate (S1P) signaling and the cystic fibrosis transmembrane conductance regulator (CFTR) as prominent regulators of myogenic responsiveness in rodent resistance arteries.
Sonya Hui +10 more
doaj +1 more source