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The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Localization of tenascin in human skin wounds [PDF]
A total of 56 surgically treated human skin wounds with a wound age between 8h and 7 months were investigated. Tenascin was visualized by immunohistochemistry and appeared first in the wound area pericellularly around fibroblastic cells approximately 2 ...
Penning, R. +4 more
core +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Telocytes in human skin – are they involved in skin regeneration? [PDF]
AbstractTelocytes (TCs), a particular interstitial cell type, have been recently described in a wide variety of mammalian organs (www.telocytes.com). The TCs are identified morphologically by a small cell body and extremely long (tens to hundreds of μm), thin prolongations (less than 100 nm in diameter, below the resolving power of light microscopy ...
Ceafalan, Laura +3 more
openaire +2 more sources
Depletion of noradrenaline inhibits electrically-evoked pain in the skin of the human forearm [PDF]
Guanethidine displaces noradrenaline from sympathetic varicosities, and blocks sympathetic noradrenergic neurotransmission by inhibiting the release of noradrenaline from depleted neural stores. The aim of this study was to determine whether depletion of
Drummond, P.D.
core
You are what you eat : Within-subject increases in fruit and vegetable consumption confer beneficial skin-color changes [PDF]
R Whitehead was funded by an ESRC Studentship.Background: Fruit and vegetable consumption and ingestion of carotenoids have been found to be associated with human skin-color (yellowness) in a recent cross-sectional study. This carotenoid-based coloration
Xiao, Dengke +15 more
core +2 more sources
Analysis of skin tissues spatial fluorescence distribution by the Monte Carlo simulation [PDF]
A novel Monte Carlo technique of simulation of spatial fluorescence distribution within the human skin is presented. The computational model of skin takes into account the spatial distribution of fluorophores, which would arise due to the structure of
Churmakov, D. Y. +3 more
core +3 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Skin microbiota and human 3D skin models [PDF]
AbstractAlthough the role of the microbiota in skin homeostasis is still emerging, there is growing evidence that an intact microbiota supports the skin barrier. The increasing number of research efforts that are trying to shed more light on the human skin‐microbiota interaction requires the use of suitable experimental models.
Franziska Rademacher +3 more
openaire +2 more sources
Background: Directional hemispherical reflectance (DHR) is a precise method for evaluating skin reflectance and is widely used in dermatological, photobiological, and cosmetic or pharmaceutical research.
Magdalena Hartman-Petrycka +3 more
doaj +1 more source

