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Molecular Basis of Human Sperm Capacitation [PDF]

Frontiers in Cell and Developmental Biology, 2018
In the early 1950s, Austin and Chang independently described the changes that are required for the sperm to fertilize oocytes in vivo. These changes were originally grouped under name of “capacitation” and were the first step in the development of in ...
Lis C. Puga Molina, Guillermina M. Luque, Paula A. Balestrini, Clara I. Marín-Briggiler, Ana Romarowski, Mariano G. Buffone   +5 more
doaj   +4 more sources

Effect of Astaxanthin on Human Sperm Capacitation [PDF]

Marine Drugs, 2013
In order to be able to fertilize oocytes, human sperm must undergo a series of morphological and structural alterations, known as capacitation. It has been shown that the production of endogenous sperm reactive oxygen species (ROS) plays a key role in ...
Luciana Bordin, Giulio Clari, Decio Armanini, Eugenio Ragazzi, Guglielmo Bonanni, Anna Maria Brunati, Guido Ambrosini, Alessandra Andrisani, Ivana Kožuh, Gabriella Donà   +9 more
doaj   +4 more sources

External quality assessment scheme for sperm DNA fragmentation: a pilot study in China

Basic and Clinical Andrology, 2023
Background The aim of this article is to establish an external quality assessment (EQA) scheme for sperm Deoxyribonucleic acid (DNA) fragmentation (SDF) detection, and to assess the feasibility of the scheme.
Yan Zheng, Ying-Bi Wu, Ye-Lin Jia, Li-Juan Ying, Ting-Ting Yang, Qing-Yuan Cheng, Jiao Qin, Chen Luo, Lin Yu, Fu-Ping Li   +9 more
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Extend the Survival of Human Sperm In Vitro in Non-Freezing Conditions: Damage Mechanisms, Preservation Technologies, and Clinical Applications

Cells, 2022
Preservation of human spermatozoa in vitro at normothermia or hypothermia maintaining their functions and fertility for several days plays a significant role in reproductive biology and medicine.
Qingyuan Cheng, Liman Li, Min Jiang, Bo Liu, Yang Xian, Shasha Liu, Xiao Liu, Wenrui Zhao, Fuping Li   +8 more
doaj   +1 more source

Effect of somatometric parameters on the prevalence and severity of varicocele: a systematic review and meta-analysis

Reproductive Biology and Endocrinology, 2021
Background Published studies have shown contradictory results regarding the relationship between somatometric parameters and varicoceles. We performed a systematic review and meta-analysis to investigate the possible effects of age, height, weight, and ...
Runqing Li, Junjie Liu, Yushan Li, Quanxian Wang   +3 more
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Human dynein and sperm pathology. [PDF]

The Journal of cell biology, 1981
Human spermatozoa with normal structure and with different axonemal deficiencies (absence of axoneme, of arms, or of central structures) were studied by electron microscopy, SDS-polyacrylamide gel electrophoresis, and ATPase activity measurements. Normal human sperm possess a complement of high molecular weight polypeptides with an electrophoretic ...
BACCETTI, B., BURRINI, A. G., PALLINI, V., RENIERI, T.   +3 more
openaire   +4 more sources

Cryopreservation of single-sperm: where are we today?

Reproductive Biology and Endocrinology, 2020
Background Patients with severe oligospermia and nonobstructive azoospermia have very limited numbers of viable sperm in their epididymal and testicular samples. Thus, cryopreservation of their sperm is performed to avoid repeated sperm retrievals and to
Shasha Liu, Fuping Li
doaj   +1 more source

“Seminal testosterone”, rising viewpoint of local spermatogenesis in nonobstructive azoospermia: One center long-term bidirectional cohort study

Frontiers in Endocrinology, 2022
ObjectiveReproductive hormones are a traditional good method to evaluate spermatogenesis but might not accurately represent local spermatogenesis. To find a more accurate method, seminal reproductive hormones were studied.MethodsA bidirectional cohort ...
Huang Liu, Houbin Zheng, Yuehua Li, Yuqian Tang, Hongbo Peng, Qianyi Li, Jiaming Zhuang, Yingyi Zhou, Yu Zhou, Xiang’an Tu, Xinzong Zhang   +10 more
doaj   +1 more source

Male cancer patient sperm cryopreservation for fertility preservation: 10-year monocentric experience

Basic and Clinical Andrology, 2021
Résumé Contexte Lacryoconservation des spermatozoïdes, méthode efficace pour préserver lafertilité masculine, est très avantageuse pour les hommes atteints de cancer.Malheureusement, comme les médecins et les patients atteints de cancersignorent les ...
Xiao Liu, Bo Liu, Shasha Liu, Yang Xian, Wenrui Zhao, Bin Zhou, Xiao Xiao, Li Wang, Xiaofang Zhu, Bizhen Shu, Min Jiang, Fuping Li   +11 more
doaj   +1 more source

Jiawei Runjing Decoction Improves Spermatogenesis of Cryptozoospermia With Varicocele by Regulating the Testicular Microenvironment: Two-Center Prospective Cohort Study

Frontiers in Pharmacology, 2022
Objective: The aim of the study was to explore the evidence of JWRJD in the treatment of cryptozoospermia.Methods: A total of 162 cryptozoospermia patients with varicocele who refused to undergo surgery were included from January 2021 to December 2021 ...
Huang Liu, Huang Liu, Zhongwang Huang, Houbin Zheng, Zhiyong Zhu, Hui Yang, Xingzhang Liu, Tao Pang, Liping He, Hai Lin, Lei Hu, Qingqi Zeng, Qingqi Zeng, Lanying Han   +13 more
doaj   +1 more source