Results 31 to 40 of about 141,242 (314)

From biological marker to clinical application: the role of anti-Müllerian hormone for delayed puberty and idiopathic non-obstructive azoospermia in males

Endocrine Connections
Anti-Müllerian hormone (AMH), a biomarker secreted by Sertoli cells in the testes, has emerged as a critical indicator of male reproductive function with significant clinical application potential.
Yuanyuan Zeng, Guicheng Zhao, Yi Zheng, Xiaohui Jiang   +3 more
doaj   +1 more source

The Effect of Glyphosate on Human Sperm Motility and Sperm DNA Fragmentation [PDF]

International Journal of Environmental Research and Public Health, 2018
Glyphosate is the active ingredient of Roundup®, which is one of the most popular herbicides worldwide. Although many studies have focused on the reproductive toxicity of glyphosate or glyphosate-based herbicides, the majority of them have concluded that the effect of the specific herbicide is negligible, while only a few studies indicate the male ...
George Anifandis, Katerina Katsanaki, Georgia Lagodonti, Christina Messini, Mara Simopoulou, Konstantinos Dafopoulos, Alexandros Daponte   +6 more
openaire   +3 more sources

Relative safety of various spermatogenic stem cell purification methods for application in spermatogenic stem cell transplantation

Stem Cell Research & Therapy, 2019
Background Spermatogonial stem cell (SSC) transplantation technology as a promising option for male fertility preservation has received increasing attention, along with efficient SSC purification technology as a necessary technical support; however, the ...
Jia Tian, Ke Ma, Cheng-bin Pei, Shao-hua Zhang, Xue Li, Yue Zhou, Bei Yan, Hong-yan Wang, Liang-hong Ma   +8 more
doaj   +1 more source

The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn2+ on CatSper Ca2+ Channels in Human Sperm

Frontiers in Cell and Developmental Biology, 2021
The sperm-specific Ca2+ channel CatSper registers chemical cues that assist human sperm to fertilize the egg. Prime examples are progesterone and prostaglandin E1 that activate CatSper without involving classical nuclear and G protein-coupled receptors ...
Janice K. Jeschke, Cristina Biagioni, Tobias Schierling, Isabel Viola Wagner, Isabel Viola Wagner, Frederik Börgel, Dirk Schepmann, Andreas Schüring, Alexandra E. Kulle, Paul Martin Holterhus, Michael von Wolff, Bernhard Wünsch, Verena Nordhoff, Timo Strünker, Timo Strünker, Christoph Brenker   +15 more
doaj   +1 more source

Cryopreservation of single-sperm from semen and testicular samples: a 5-year monocentric experience in hundreds of patients

Reproductive Biology and Endocrinology
For patients with severe oligozoospermia, cryopreservation of single human spermatozoa highlights its advantages. Previous research has focused on the development of micro-drop single sperm freezing methods with non-biological carriers over the past 20 ...
Shasha Liu, Jinyan Xu, Bo Liu, Yang Xian, Min Jiang, Fuping Li   +5 more
doaj   +1 more source

Post-Meiotic Intra-Testicular Sperm Senescence in a Wild Vertebrate

, 2012
There is growing interest in sperm senescence, both in its underlying mechanisms and evolutionary consequences, because it can impact the evolution of numerous life history traits. Previous studies have documented various types of sperm senescence, but
Richard H. Wagner, Penn, Dustin J., Richard H Wagner, Hoi Herbert, Wagner, Richard H., Hettyey Attila, Hoi, Herbert, Attila Hettyey, Dustin J. Penn, Balázs Vági, Herbert Hoi, Vági Balázs, Wagner Richard H., Penn Dustin J., Hettyey, Attila, Vági, Balázs, Dustin J Penn   +16 more
core   +1 more source

Expression of Tas1 taste receptors in mammalian spermatozoa [PDF]

, 2012
Background: During their transit through the female genital tract, sperm have to recognize and discriminate numerous chemical compounds. However, our current knowledge of the molecular identity of appropriate chemosensory receptor proteins in sperm is ...
Ulrich Boehm (180339), de Angelis Martin Hrabé, Breit, A., Dorke Meyer, Andreas Breit (180329), Hrabě de Angelis, M., Widmayer Patricia, Wolfgang Meyerhof, Boekhoff Ingrid, Boehm, Ulrich, Martin Hrabé de Angelis, Meyer, Dorke, Ulrich Boehm, Dorke Meyer (180311), Sandra Huebner, Gudermann, T., Boehm, U., Borth, Heike, Borth Heike, Meyerhof, Wolfgang, Susan Marschall, Huebner Sandra, Voigt, Anja, Meyerhof, W., Hrabé de Angelis, Martin, Huebner, S., Sandra Huebner (180323), Thomas Gudermann (77426), Huebner, Sandra, Heike Borth, Borth, H., Susan Marschall (180334), Meyerhof Wolfgang, Ingrid Boekhoff, Ingrid Boekhoff (180345), Heike Borth (180317), Andreas Breit, Meyer Dorke, Boekhoff, I., Voigt Anja, Thomas Gudermann, Anja Voigt, Voigt, A., Gudermann Thomas, Breit Andreas, Boehm Ulrich, Marschall Susan, Marschall, Susan, Widmayer, Patricia, Widmayer, P., Wolfgang Meyerhof (7851), Patricia Widmayer, Martin Hrabé de Angelis (10007), Patricia Widmayer (180314), Breit, Andreas, Boekhoff, Ingrid, Gudermann, Thomas, Anja Voigt (173059), Marschall, S., Meyer, D.   +59 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Comparison of outcomes between pulsatile gonadotropin releasing hormone and combined gonadotropin therapy of spermatogenesis in patients with congenital hypogonadotropic hypogonadism

Reproductive Biology and Endocrinology
Background To evaluate whether there was a difference in outcome between pulsatile gonadotropin releasing hormone (GnRH) therapy and human chorionic gonadotropin/human menopausal gonadotropin (hCG/HMG) therapy for induction of spermatogenesis in post ...
Yi Zheng, Heng-Zhou Bai, Gui-Cheng Zhao, Kun Tian, Jun-Tao Yue, Ding-Ming Li, Xiao-Hui Jiang   +6 more
doaj   +1 more source

The legacy of sperm banking: how fertility monitoring and disposal of sperm are linked with views of cancer treatment

, 2011
Background: sperm banking is recommended for all men before cancer treatment, which carries a risk of long-term gonadal damage. However, relatively few men take up the offer.
Arden-Close, Emily, C. Eiser, Eiser, C., Pacey, A.A., Pacey, A. A.; id_orcid, Morris, K., E. Arden-Close, K. Morris, A. A. Pacey, Arden-Close, E.   +9 more
core   +1 more source