Results 21 to 30 of about 24,961 (206)

Inability to Detect Human T Cell Lymphotropic Virus Type 2-Specific Antibodies in a Patient Coinfected with HIV-1, Human T Cell Lymphotropic Virus Type 1, Human T Cell Lymphotropic Virus Type 2, and Hepatitis C Virus [PDF]

AIDS Research and Human Retroviruses, 2014
HIV-1, human T cell lymphotropic virus type 1 and type 2 (HTLV-1 and HTLV-2) and hepatitis C virus (HCV) are common among intravenous drug users (IDUs) and can cause chronic infections in the host. Usually, the diagnosis of such viruses employs serological assays; however, some difficulties in confirming HTLV-2 infection have been reported in high-risk
Adele, Caterino-de-Araujo, Mariana Cavalheiro, Magri, Neuza Satomi, Sato, Helena Kaminami, Morimoto, Luis Fernando de Macedo, Brigido, Arilson Akira, Morimoto   +5 more
openaire   +2 more sources

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures

Nature Communications, 2021
Human T-cell lymphotropic virus type 1 (HTLV-1) is an oncogenic deltaretrovirus. Here the authors provide structural characterization of the binding mechanism of novel integrase strand transfer inhibitor (INSTI) candidates to limit HTLV-1 infection.
Michal S. Barski, Teresa Vanzo, Xue Zhi Zhao, Steven J. Smith, Allison Ballandras-Colas, Nora B. Cronin, Valerie E. Pye, Stephen H. Hughes, Terrence R. Burke, Peter Cherepanov, Goedele N. Maertens   +10 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Dengue fever and human T-cell lymphotropic virus type 1 infection [PDF]

International Journal of Infectious Diseases, 2013
Globalization has increased both the number of emergent diseases and the diversity of co-infections, which could in turn mutually influence the pathogenesis of well-known infectious diseases. Here, we report the first series of chronic human T-cell lymphotropic virus type 1 (HTLV-1) patients co-infected with the dengue fever virus.
Longo, Cecília Lameirinhas, Brasil, Patricia, Espíndola, Otávio de Melo, Leite, Ana Claudia Celestino Bezerra, Nogueira, Rita Maria Ribeiro, Lupi, Otília, Neves, Elizabeth de Souza   +6 more
openaire   +2 more sources

Variant Human T-cell Lymphotropic Virus Type 1c and Adult T-cell Leukemia, Australia

Emerging Infectious Diseases, 2013
Human T-cell lymphotropic virus type 1 is endemic to central Australia among Indigenous Australians. However, virologic and clinical aspects of infection remain poorly understood.
Lloyd Einsiedel, Olivier Cassar, Peter Bardy, Daniel Kearney, Antoine Gessain   +4 more
doaj   +1 more source

Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

Nature Communications, 2020
Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.
Michał S. Barski, Jordan J. Minnell, Zuzana Hodakova, Valerie E. Pye, Andrea Nans, Peter Cherepanov, Goedele N. Maertens   +6 more
doaj   +1 more source

Particularities of Neurological Manifestations in Adult T-Cell Leukemia/Lymphoma: Need for a Multidisciplinary Approach—A Narrative Review

Medicina, 2022
ATL is a rare but a highly aggressive T-cell neoplasm associated with human T-cell leukemia virus-1 (HTLV-1) infection. Human T-cell lymphotropic virus type-1 (HTLV-1) is a oncogenic retrovirus responsible for the development of adult T-cell leukemia ...
Iuliana Iordan, Minodora Onisâi, Ana-Maria Vlădăreanu, Cristina Mambet, Elena Cristina Marinescu, Raluca Nistor, Horia Bumbea   +6 more
doaj   +1 more source

HIV-1 and HTLV-1 Transmission Modes: Mechanisms and Importance for Virus Spread

Viruses, 2022
So far, only two retroviruses, human immunodeficiency virus (HIV) (type 1 and 2) and human T-cell lymphotropic virus type 1 (HTLV-1), have been recognized as pathogenic for humans. Both viruses mainly infect CD4+ T lymphocytes.
Svetlana Kalinichenko, Dmitriy Komkov, Dmitriy Mazurov   +2 more
doaj   +1 more source

Neuropilin-1 Is Involved in Human T-Cell Lymphotropic Virus Type 1 Entry [PDF]

Journal of Virology, 2006
ABSTRACTHuman T-cell lymphotropic virus type 1 (HTLV-1) is transmitted through a viral synapse and enters target cells via interaction with the glucose transporter GLUT1. Here, we show that Neuropilin-1 (NRP1), the receptor for semaphorin-3A and VEGF-A165 and a member of the immune synapse, is also a physical and functional partner of HTLV-1 envelope ...
David, Ghez, Yves, Lepelletier, Sophie, Lambert, Jean-Marie, Fourneau, Vincent, Blot, Sébastien, Janvier, Bertrand, Arnulf, Peter M, van Endert, Nikolaus, Heveker, Claudine, Pique, Olivier, Hermine   +10 more
openaire   +2 more sources

Small cells lung epidermoid carcinoma in a HTLV1-infected patient: case report and literature review

Revista do Instituto de Medicina Tropical de São Paulo, 2021
The human T cell lymphotropic virus type 1 (HTLV-1) is the first human retrovirus discovered. Since then, it has spread worldwide and is mainly associated with adult T cell leukemia/lymphoma (ATLL) and HTLV1-associated myelopathy (HAM). Its relationship,
Flávia Esper Dahy, Renata Basic Palhares, Tatiane Assone, Jerusa Smid, João Victor Luisi de Moura, Michel E. J. Haziot, Rosa Maria N. Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb   +8 more
doaj   +1 more source