Results 21 to 30 of about 23,287 (168)

Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

Nature Communications, 2020
Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.
Michał S. Barski, Jordan J. Minnell, Zuzana Hodakova, Valerie E. Pye, Andrea Nans, Peter Cherepanov, Goedele N. Maertens   +6 more
doaj   +1 more source

Particularities of Neurological Manifestations in Adult T-Cell Leukemia/Lymphoma: Need for a Multidisciplinary Approach—A Narrative Review

Medicina, 2022
ATL is a rare but a highly aggressive T-cell neoplasm associated with human T-cell leukemia virus-1 (HTLV-1) infection. Human T-cell lymphotropic virus type-1 (HTLV-1) is a oncogenic retrovirus responsible for the development of adult T-cell leukemia ...
Iuliana Iordan, Minodora Onisâi, Ana-Maria Vlădăreanu, Cristina Mambet, Elena Cristina Marinescu, Raluca Nistor, Horia Bumbea   +6 more
doaj   +1 more source

Neuropilin-1 Is Involved in Human T-Cell Lymphotropic Virus Type 1 Entry [PDF]

Journal of Virology, 2006
ABSTRACTHuman T-cell lymphotropic virus type 1 (HTLV-1) is transmitted through a viral synapse and enters target cells via interaction with the glucose transporter GLUT1. Here, we show that Neuropilin-1 (NRP1), the receptor for semaphorin-3A and VEGF-A165 and a member of the immune synapse, is also a physical and functional partner of HTLV-1 envelope ...
David, Ghez, Yves, Lepelletier, Sophie, Lambert, Jean-Marie, Fourneau, Vincent, Blot, Sébastien, Janvier, Bertrand, Arnulf, Peter M, van Endert, Nikolaus, Heveker, Claudine, Pique, Olivier, Hermine   +10 more
openaire   +2 more sources

HIV-1 and HTLV-1 Transmission Modes: Mechanisms and Importance for Virus Spread

Viruses, 2022
So far, only two retroviruses, human immunodeficiency virus (HIV) (type 1 and 2) and human T-cell lymphotropic virus type 1 (HTLV-1), have been recognized as pathogenic for humans. Both viruses mainly infect CD4+ T lymphocytes.
Svetlana Kalinichenko, Dmitriy Komkov, Dmitriy Mazurov   +2 more
doaj   +1 more source

Gastric strongyloidiasis and infection by the human T cell lymphotropic virus type 1 (HTLV-1) [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2003
José Roberto Lambertucci, Flávia Costa Carvalho Leão, Alfredo José Afonso Barbosa   +2 more
doaj   +5 more sources

Small cells lung epidermoid carcinoma in a HTLV1-infected patient: case report and literature review

Revista do Instituto de Medicina Tropical de São Paulo, 2021
The human T cell lymphotropic virus type 1 (HTLV-1) is the first human retrovirus discovered. Since then, it has spread worldwide and is mainly associated with adult T cell leukemia/lymphoma (ATLL) and HTLV1-associated myelopathy (HAM). Its relationship,
Flávia Esper Dahy, Renata Basic Palhares, Tatiane Assone, Jerusa Smid, João Victor Luisi de Moura, Michel E. J. Haziot, Rosa Maria N. Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb   +8 more
doaj   +1 more source

Geographical clustering of human T-cell lymphotropic virus type 1 infection in Honduras [PDF]

Journal of Clinical Microbiology, 1995
Geographical clustering of human T-cell lymphotropic virus type 1 (HTLV-1) infection has been identified in the nonmestizo communities in several cities along the Atlantic coast of Honduras. Of the 2,651 serum samples tested, 122 samples were repeatedly reactive for HTLV-1 antibodies in two different enzyme immunoassays and 3 were indeterminate.
I L, de Rivera, L, Amador, S, Mourra, Z, Li, S, Rasheed   +4 more
openaire   +2 more sources

Human T‐Cell Lymphotropic Virus Type 1 and associated diseases in Latin America [PDF]

Tropical Medicine & International Health, 2019
SummaryThis narrative review, which is based on a systematic literature search following the PRISMA guidelines, provides a general overview of Human T‐cell Lymphotropic Virus type 1 (HTLV‐1) and associated diseases: Adult T‐cell Leukaemia–Lymphoma (ATLL) and HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) in Latin America, focusing ...
Eusebio-Ponce, Emiliana, Candel, Francisco Javier, Anguita, Eduardo   +2 more
openaire   +3 more sources

Hairy Projections on Non Hairy Cells- A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2021
Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2,
Rhituparna Das, Sriranjan Mukherjee, Moumita Sengupta   +2 more
doaj   +1 more source

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects

Viruses, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Benjamin Usadi, Roberta Bruhn, Jue Lin, Tzong-Hae Lee, Elizabeth Blackburn, Edward L. Murphy   +5 more
doaj   +1 more source