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Human T-lymphotropic virus type 1 infection
Best Practice & Research Clinical Haematology, 2000Human T-cell lymphotropic virus type-1 (HTLV-1) is aetiologically associated with adult T-cell leukaemia/lymphoma (ATL). HTLV-1 infection can also lead to various non-malignant diseases, for example, HTLV-1 associated myelopathy/tropical spastic paraparesis and HTLV-1 uveitis. HTLV-1 is endemic in southern Japan and the Caribbean.
K, Tsukasaki, P, Koeffler, M, Tomonaga
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Human T-lymphotropic virus 1 neurologic disease
Current Treatment Options in Neurology, 2008Human T-lymphotrophic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a disabling myelopathy, but clinical trials of specific drugs to treat it are lacking. There are many reasons for the absence of specific therapeutic studies, including difficulty in enrolling patients, inadequate measurement tools to evaluate ...
Abelardo, Araújo +2 more
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Primary Human T-Lymphotropic Virus Type III Infection
Annals of Internal Medicine, 1985Primary infection with the human T-lymphotropic virus type III (HTLV-III) was documented in three patients by virus isolation during acute illness and concurrent or subsequent HTLV-III seroconversion. All patients had fevers, rigors, arthralgias, and myalgias.
D D, Ho +5 more
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Human T-lymphotropic virus/HIV co-infection
Current Opinion in Infectious Diseases, 2014Human T-lymphotropic virus (HTLV)/HIV co-infections are often undiagnosed, with important clinical implications. The literature is relatively sparse with key observations derived in the pre-highly-active antiretroviral therapy era.The epidemiology of co-infection, the impact of each virus on the other, with particular reference to clinical ...
Divya, Dhasmana, Graham P, Taylor
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Transfusion transmitted human T‐lymphotropic virus infections
Acta Anaesthesiologica Scandinavica, 1988Human immunodeficiency virus (HIV) type 1 has emerged during the 1980s as an important transfusion transmitted agent. The impact of HIV depends on the epidemiology and characteristics of the virus, serological response to infection and efficacy of serological tests to identify infected blood units. These factors will be described in the present article.
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Human T-lymphotropic virus type I in Japan
The Lancet, 1994Adult T-cell leukaemia (ATL) was first reported in Japan, where it has a high incidence in the southwest region. The retrovirus human T-lymphotropic virus type I (HTLV-I) is the cause of ATL; and in ATL-endemic areas, the rate of carriage of antibodies to HTLV-I is high. A definite diagnosis of ATL is based on the presence of HTLV-I proviral DNA in the
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Infection of defective human T-lymphotropic virus type 1
Human Cell, 2017In a previous study, we reported that an identical defective provirus had integrated into multiple sites of the genome of a representative human T-lymphotropic virus type 1 (HTLV-1) cell line, MT-2. A possible explanation for this may be the repeated infection of this defective provirus to a cell.
Yuuki, Hashikura +8 more
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Manifestations of human T-lymphotropic virus type I infection
The American Journal of Medicine, 1988HTLV-I, the first human oncovirus, is a type C retrovirus linked to the development of ATLL. The virus shows a striking ethnogeographic distribution that is only partially understood. Certain populations at high risk for AIDS appear to have a higher incidence of HTLV-I infection.
J H, Kim, D T, Durack
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Human T‐lymphotropic virus type II and neurological disease
Annals of Neurology, 2004AbstractHuman T‐lymphotropic virus type I (HTLV‐I) and type II (HTLV‐II) are closely related retroviruses with similar biological properties and common modes of transmission. HTLV‐I infection is endemic in well‐defined geographic regions, and it is estimated that some 20 million individuals are infected worldwide. Although most infected individuals are
Abelardo, Araujo, William W, Hall
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Antigens of Human T-Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus
Annals of Internal Medicine, 1985Antigens encoded by the gag and env genes of the human T-lymphotropic virus type III/lymphadenopathy associated virus (HTLV-III/LAV) include a p55 gag polyprotein that yields p24 as the major virus core protein, and an env gene polyprotein, gp 160, that produces gp 120, the most immunogenic protein in humans, at the amino terminus.
M, Essex +6 more
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